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Treatment moderators and predictors of outcome in the Treatment of Early Age Mania (TEAM) study.

Author: AxelsonDavid A, BirmaherBoris, EmslieGraham, JoshiParamjit, LubyJoan, RiddleMark A, RobbAdelaide, RyanNeal D, TillmanRebecca, VitielloBenedetto, WagnerKaren D, WalkupJohn T, YenokyanGayane

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

Treating bipolar disorder in children is challenging. In a study called TEAM, the medication risperidone was more effective than lithium or divalproex in children with bipolar mania, especially those with attention-deficit/hyperactivity disorder (ADHD). This research aims to identify factors that might predict how well children respond to treatment and what might make treatment more effective.
Paper Details　
Original Abstract of the Article :
Both the diagnosis and treatment of bipolar disorder in youth remain the subject of debate. In the Treatment of Early Age Mania (TEAM) study, risperidone was more effective than lithium or divalproex in children diagnosed with bipolar mania and highly comorbid with attention-deficit/hyperactivity di...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/22917200

データ提供：米国国立医学図書館（NLM）

Bipolar Disorder in Youth: A Complex and Evolving Landscape

Bipolar disorder in youth is a complex and challenging condition that requires careful diagnosis and management. This research investigates the treatment of early age mania (TEAM) study, a clinical trial that compared the effectiveness of risperidone, lithium, and divalproex in children with bipolar mania. The study found that risperidone was more effective than lithium or divalproex in children with high comorbidity with attention-deficit/hyperactivity disorder (ADHD). This research highlights the need for individualized treatment approaches based on the specific characteristics of the patient and their co-occurring conditions.

Tailoring Treatment to Individual Needs: A Journey Through the Desert of Bipolar Disorder

The TEAM study findings underscore the importance of considering the specific characteristics of each individual with bipolar disorder, including their co-occurring conditions, when determining the most effective treatment approach. This research emphasizes the need for a personalized approach to care, ensuring that treatment plans are tailored to the unique needs of each patient.

Navigating the Desert of Bipolar Disorder

This research provides valuable insights into the treatment of bipolar disorder in youth, emphasizing the need for careful diagnosis, individualized treatment approaches, and ongoing monitoring to ensure the best possible outcomes for patients. Just like the desert presents unique challenges, bipolar disorder requires a comprehensive and personalized approach to ensure a safe and successful journey through treatment.

Dr.Camel's Conclusion

This research sheds light on the complex and evolving landscape of bipolar disorder in youth, highlighting the importance of individualizing treatment approaches based on specific characteristics and co-occurring conditions. It emphasizes the need for ongoing research to refine treatment strategies and improve outcomes for this challenging condition. Just like the desert presents unique challenges, bipolar disorder requires a comprehensive and personalized approach to ensure a safe and successful journey through treatment.

Date :
  1. Date Completed 2013-01-16
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

22917200

DOI: Digital Object Identifier

NIHMS393014

Related Literature

Article Analysis
・Effective treatment of bipolar disorder
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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