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Weekly topotecan for recurrent small cell lung cancer - a retrospective Anatolian Medical Oncology Group study.
Author: AliciSuleyman, AltinbasMustafa, ArpaciErkan, CamciCelalettin, GumusMahmut, KalenderMehmet Emin, KaplanM Ali, KaracaHalit, OvenBasak, SevincAlper, UncuDogan, YildizRamazan
Original Abstract of the Article :
AIM: To evaluate efficacy and tolerability of topotecan treatment for recurrent small cell lung carcinoma. PATIENTS AND METHODS: A total of 62 patients were evaluated retrospectively. Statistical analysis was performed using GraphPad Instat (version 3.05). RESULTS: Fifty five patients (89%) were m...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.7314/apjcp.2012.13.6.2909
データ提供:米国国立医学図書館(NLM)
Fighting a Tough Battle: Recurrent Small Cell Lung Cancer
Lung cancer is a formidable adversary, and its recurrence can be particularly challenging. This retrospective Anatolian Medical Oncology Group study examines the effectiveness and side effects of topotecan, a chemotherapy drug, in treating recurrent small cell lung cancer (SCLC). The study analyzes patient data to understand how this treatment fares in the battle against this aggressive form of cancer.
Looking Back to Move Forward
The study found that topotecan was a viable treatment option for recurrent SCLC. Patients who were younger and had later recurrences tended to respond better to topotecan. However, the study highlights the importance of careful consideration of both hematological and non-hematological side effects associated with this chemotherapy. This study provides valuable insights into the use of topotecan, aiding in the development of personalized treatment plans for patients with recurrent SCLC.
Navigating the Treatment Landscape
The battle against lung cancer is ongoing, and this study underscores the need for personalized treatment approaches. The researchers emphasize the importance of understanding the specific characteristics of each patient and tailoring treatment plans accordingly. While topotecan offers a potential weapon in this fight, its use should be carefully considered and monitored to minimize potential side effects.
Dr. Camel's Conclusion
Lung cancer is a formidable foe, like a sandstorm that can quickly engulf the desert. This study provides valuable insights into the use of topotecan, a tool that can help us weather the storm and navigate the complexities of recurrent SCLC. Careful consideration of individual patient characteristics is crucial in the fight against this challenging disease.
Date :
- Date Completed 2013-02-27
- Date Revised 2019-06-06
Further Info :
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