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Growth hormone treatment in boys with Duchenne muscular dystrophy and glucocorticoid-induced growth failure.
Author: CollinsJames, CripeLinda H, HorKan N, RoseSusan R, RutterMeilan M, SawnaniHemant, SucharewHeidi, WongBrenda L, WooJessica G
Original Abstract of the Article :
This study evaluated efficacy and safety of growth hormone treatment in Duchenne muscular dystrophy boys with glucocorticoid-induced growth failure. We reviewed 39 consecutive boys (average age 11.5 years; 32 ambulatory) treated with growth hormone for 1 year during a four-year period. Boys were on ...See full text at original site
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引用元:
https://doi.org/10.1016/j.nmd.2012.07.009
データ提供:米国国立医学図書館(NLM)
Growth Hormone Treatment for Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is a severe genetic disorder that causes progressive muscle weakness and degeneration. This research examines the effectiveness of growth hormone treatment for boys with DMD who have experienced growth failure due to glucocorticoid therapy. The study delves into the impact of growth hormone on growth velocity, height-for-age z-scores, and other important clinical outcomes, while also assessing the safety of this treatment. The authors present a review of 39 consecutive boys with DMD who received growth hormone therapy, offering valuable insights into its potential benefits and risks.
Growth Hormone Improves Growth in Boys with DMD
The study reveals that growth hormone treatment significantly improved growth velocity and stabilized height-for-age z-scores in boys with DMD and glucocorticoid-induced growth failure. The authors report a substantial increase in growth velocity and a marked improvement in height, suggesting that growth hormone can effectively address the growth challenges associated with DMD and glucocorticoid therapy. These findings offer a glimmer of hope for improving the overall well-being of boys with DMD.
Managing DMD: Optimizing Treatment and Quality of Life
DMD is a complex and challenging condition that requires a comprehensive approach to management. This study highlights the importance of considering growth hormone therapy as a potential treatment option for boys with DMD who are experiencing growth failure. By addressing growth issues and improving overall well-being, healthcare providers can enhance the quality of life for boys with DMD and optimize their overall care.
Dr. Camel's Conclusion
The desert of DMD can be a difficult journey, with challenges related to muscle weakness and growth impairment. This study sheds light on the potential benefits of growth hormone therapy in improving growth and overall well-being for boys with DMD. By understanding the potential of this treatment and working closely with their healthcare team, patients can find their way toward a brighter future, navigating the desert of DMD with greater strength and resilience.
Date :
- Date Completed 2013-06-12
- Date Revised 2013-11-21
Further Info :
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