Paper Details

  1. Home
  2. Paper Details

Dutasteride treatment over 2 years delays prostate-specific antigen progression in patients with biochemical failure after radical therapy for prostate cancer: results from the randomised, placebo-controlled Avodart After Radical Therapy for Prostate Cancer Study (ARTS).

Author: AlcarazAntonio, AnguloJavier C, BangmaChris, CastroRamiro, ColombelMarc, McNicholasTom, NandyIndrani, SchröderFritz, TammelaTeuvo L

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study highlights the challenges of managing prostate cancer (PCa) that returns after initial treatment. An increase in PSA levels after treatment indicates that the cancer may be recurring or that some cancer cells remain. This recurrence often occurs years before the cancer is visible on imaging, making treatment decisions difficult. The study notes that there is no single agreed-upon approach for treating recurrent PCa.
Paper Details　
Original Abstract of the Article :
Rising prostate-specific antigen (PSA) levels after radical therapy are indicative of recurrent or residual prostate cancer (PCa). This biochemical recurrence typically predates clinically detectable metastatic disease by several years. Management of patients with biochemical recurrence is controver...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.eururo.2012.11.006

データ提供：米国国立医学図書館（NLM）

Dutasteride Treatment for Biochemical Failure After Prostate Cancer

Prostate cancer, like a persistent desert wind eroding the landscape of the prostate, can be a challenging condition to manage. This study, much like a group of researchers testing different methods to control the wind's destructive power, investigates the effectiveness of dutasteride treatment in patients with biochemical failure after radical therapy for prostate cancer.

A New Weapon in the Fight Against Prostate Cancer

This study, like a strategically placed sand dune blocking the wind's advance, explores the potential of dutasteride treatment in delaying prostate-specific antigen (PSA) progression in patients with biochemical failure after radical therapy for prostate cancer. The researchers find that dutasteride treatment significantly delays PSA progression, offering a valuable tool in the fight against this challenging condition.

Harnessing the Power of Time

This study, like a patient and persistent desert wanderer, emphasizes the importance of slowing the progression of prostate cancer. The researchers' findings highlight the potential of dutasteride treatment to buy patients valuable time, allowing for more effective management and potentially delaying the need for more invasive treatments. This approach emphasizes the importance of harnessing the power of time in the fight against this disease.

Dr.Camel's Conclusion

Prostate cancer can be a relentless adversary, much like a persistent desert wind that slowly erodes the landscape. This study offers a promising new weapon in the fight against this disease, highlighting the potential of dutasteride treatment to delay PSA progression. By harnessing the power of time, we can equip patients with the tools to manage their condition more effectively and potentially delay the need for more aggressive therapies.
Date :
  1. Date Completed 2013-09-24
  2. Date Revised 2021-11-22
Further Info :

Pubmed ID

23176897

DOI: Digital Object Identifier

10.1016/j.eururo.2012.11.006

Related Literature

Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.