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The role of cytokines in acute myeloid leukemia: a systematic review.

Author: HoracekJan Milos, JebavyLadislav, KupsaTomas

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Acute myeloid leukemia (AML) is a complex cancer with different forms. Current treatments, while effective for many patients, don't always work for everyone, even with high-dose chemotherapy. The harsh effects of chemotherapy lead to severe side effects and increase the risk of infections, making it difficult to increase the dose.
Paper Details　
Original Abstract of the Article :
Acute myeloid leukemia (AML) shows a high degree of heterogeneity owing to a variety of mutations and the mechanisms of leukemogenesis. This heterogeneity is often not reflected in standard treatment approaches which while providing predictable outcomes in the majority of patients fail in particular...See full text at original site
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引用元：
https://doi.org/10.5507/bp.2012.108

データ提供：米国国立医学図書館（NLM）

Cytokines in Acute Myeloid Leukemia: A Complex Role

Acute myeloid leukemia (AML) is a type of cancer that affects the blood and bone marrow. It's a complex disease with many different subtypes, each with its own unique characteristics. This study explores the role of cytokines, small signaling molecules, in AML.

Cytokines and AML: A Delicate Balance

The authors provide a comprehensive overview of the complex relationship between cytokines and AML. They discuss how cytokines play a role in the development and progression of the disease, highlighting the heterogeneity of AML and the challenges of developing effective treatments.

Improving AML Treatment

This review emphasizes the need for a more personalized approach to AML treatment, taking into account the unique characteristics of each subtype of the disease. It highlights the potential of understanding the role of cytokines in developing more targeted and effective therapies.

Dr. Camel's Conclusion

This review provides a glimpse into the intricate world of cytokines and their role in AML. Like a camel navigating a vast and ever-changing desert, understanding the complex interactions within the body is essential for finding effective treatments. This research serves as a reminder of the ongoing pursuit of new and innovative therapies to improve the lives of patients with AML.

Date :
  1. Date Completed 2014-03-12
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

23223353

DOI: Digital Object Identifier

10.5507/bp.2012.108

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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