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Methotrexate for induction of remission in refractory Crohn's disease.

Author: FeaganBrian G, MacdonaldJohn K, McDonaldJohn W D, TsoulisDavid J

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This study examines the use of methotrexate as a treatment for Crohn's disease that does not respond to steroids. While steroids are effective initially, many patients experience a return of symptoms or become reliant on steroids, which have significant side effects. The study provides an update on research about methotrexate, which has become a common alternative treatment for Crohn's disease that does not respond to other medications.
Paper Details　
Original Abstract of the Article :
Although corticosteroids are effective for induction of remission of Crohn's disease, many patients relapse when steroids are withdrawn or become steroid dependent. Furthermore, corticosteroids exhibit significant adverse effects. The success of methotrexate as a treatment for rheumatoid arthritis l...See full text at original site
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引用元：
https://doi.org/10.1002/14651858.CD003459.pub3

データ提供：米国国立医学図書館（NLM）

Methotrexate for Refractory Crohn's Disease: A Promising Alternative

This study explores the use of methotrexate, a medication known for its effectiveness in rheumatoid arthritis, as a treatment for refractory Crohn's disease. Think of this as a desert explorer seeking a new path through a treacherous landscape. Methotrexate has emerged as a potential alternative to traditional treatments like corticosteroids, which can have significant side effects. The research reviewed a variety of studies on methotrexate's effectiveness in inducing remission, suggesting its value in managing this challenging condition.

A New Path in Crohn's Disease Treatment

The study underscores the potential benefits of methotrexate for managing refractory Crohn's disease. It provides a compelling argument for considering methotrexate as an alternative to corticosteroids, potentially offering a safer and more effective treatment option.

Hope for Improved Patient Outcomes

This research opens doors to new possibilities for patients with refractory Crohn's disease. Methotrexate's potential to induce remission offers a glimmer of hope for improved patient outcomes and a better quality of life.

Dr.Camel's Conclusion

This research sheds light on methotrexate's potential as a promising alternative treatment for refractory Crohn's disease. Its effectiveness in inducing remission and its relatively lower side effect profile compared to corticosteroids offer a new path for managing this challenging condition. Further research is needed to fully explore its therapeutic potential and optimize its use for patients.

Date :
  1. Date Completed 2013-02-21
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

23235598

DOI: Digital Object Identifier

10.1002/14651858.CD003459.pub3

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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