Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial.

Author: HajheydariZohreh, Morteza-SemnaniKatayoun, SaeediMajid, SoltaniAida

Paper Details 
Original Abstract of the Article :
BACKGROUND: Topical retinoids are considered first-line therapy in the treatment of acne vulgaris, yet can be associated with cutaneous irritations. Combination therapy with natural preparations could be effective in treatment and decreasing adverse events. OBJECTIVE: The aim of this study was to c...See full text at original site
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引用元:
https://doi.org/10.3109/09546634.2013.768328

データ提供:米国国立医学図書館(NLM)

Combining Treatments for Acne: Aloe Vera and Tretinoin

Acne vulgaris is a common skin condition, often causing frustration and discomfort. This study explores the potential of combining tretinoin, a topical retinoid, with Aloe vera gel to treat mild to moderate acne vulgaris. The researchers conducted a randomized, double-blind, prospective trial to compare the efficacy and safety of this combination therapy with tretinoin alone and a placebo.

A Multifaceted Approach to Acne Treatment

The study's findings suggest that combining tretinoin with Aloe vera gel can be more effective than using tretinoin alone for treating mild to moderate acne. The researchers observed a significant reduction in both inflammatory and non-inflammatory acne lesions among patients receiving the combination therapy compared to those receiving tretinoin alone. Moreover, the combination therapy was well-tolerated, with fewer instances of erythema (redness) compared to tretinoin alone.

A Natural Oasis for Clear Skin

This research highlights the potential of incorporating natural ingredients like Aloe vera into acne treatment regimens. The study's findings suggest that combining tretinoin with Aloe vera gel can improve treatment outcomes and reduce side effects, offering a more comfortable and effective approach to managing acne. This study serves as a reminder that the desert of skincare is vast and diverse, with natural ingredients often holding valuable therapeutic potential.

Dr.Camel's Conclusion

This study is like a refreshing oasis in the desert of acne treatments. The combination of tretinoin and Aloe vera gel offers a promising approach to managing acne, providing both efficacy and tolerability. This study serves as a reminder that exploring natural ingredients can lead to innovative and effective treatment strategies for a wide range of conditions.

Date :
  1. Date Completed 2014-04-08
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

23336746

DOI: Digital Object Identifier

10.3109/09546634.2013.768328

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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