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Surgical implantation of steroids with antiangiogenic characteristics for treating neovascular age-related macular degeneration.

Author: GeltzerArthur, TuralbaAngela, VedulaSatyanarayana S

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

A review of three randomized controlled trials found no evidence that antiangiogenic steroids prevent visual loss in patients with neovascular age-related macular degeneration (AMD). Further research is needed to determine the role of steroids in the treatment of neovascular AMD.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Neovascular age-related macular degeneration (AMD) is associated with rapid vision loss due to choroidal neovascularization (CNV), leakage, and scarring. Steroids have gained attention in their role for the treatment of neovascular AMD for their antiangiogenic and anti-inflammatory prope...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/23440797

データ提供：米国国立医学図書館（NLM）

Steroids and Neovascular Age-Related Macular Degeneration

In the vast desert of vision loss, we're exploring the potential of steroids in treating a specific type of age-related macular degeneration (AMD). This research, a detailed exploration of the landscape of AMD treatment, examines the use of steroids with antiangiogenic properties. It's like searching for a hidden oasis in the desert, a cure for a vision-threatening condition.

A Comprehensive Search for Effective Treatment

This study meticulously reviewed numerous clinical trials, a task akin to mapping a vast and intricate desert. The researchers meticulously analyzed the data, searching for evidence of steroids' effectiveness in halting vision loss in patients with neovascular AMD.

Limited Evidence and Emerging Treatments

The results of this study, while not conclusive, highlight the need for further research in this area. It's like a desert traveler finding a promising oasis only to discover it's a mirage. While steroids show promise, the emergence of anti-vascular endothelial growth factor modalities offers a new avenue for treatment. The authors suggest that the role of steroids in AMD treatment remains unclear and warrants further investigation.

Dr.Camel's Conclusion

The journey to understanding the role of steroids in treating neovascular AMD is ongoing. Like a desert explorer, we continue to explore new pathways and possibilities in the search for effective treatments. This study serves as a reminder that the quest for vision-saving therapies requires persistent research and a commitment to finding solutions.

Date :
  1. Date Completed 2013-03-12
  2. Date Revised 2023-11-10
Further Info :

Pubmed ID

23440797

DOI: Digital Object Identifier

NIHMS644974

Related Literature

Article Analysis
・Effective treatment of macular degeneration
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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