Selected pregnancy and delivery outcomes after exposure to antidepressant medication: a systematic review and meta-analysis.

Author: CheungAmy, DennisCindy-Lee, GrigoriadisSophie, KorenGideon, MamisashviliLana, MousmanisPatricia, RehmJürgen, RoereckeMichael, RossLori E, SteinerMeir, VonderportenEmily H

Paper Details 
Original Abstract of the Article :
IMPORTANCE: Untreated depression during pregnancy has been associated with increased morbidity and mortality for both mother and child and, as such, optimal treatment strategies are required for this population. CONTEXT: There are conflicting data regarding potential risks of prenatal antidepressan...See full text at original site
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引用元:
https://doi.org/10.1001/jamapsychiatry.2013.684

データ提供:米国国立医学図書館(NLM)

Navigating Pregnancy: Antidepressant Use and Maternal Health

The use of antidepressant medication during pregnancy is a complex issue, with concerns surrounding potential risks to both mother and child. This study delves into the relationship between prenatal antidepressant exposure and selected pregnancy and delivery outcomes, aiming to provide a comprehensive overview of the existing evidence. The authors conducted a systematic review and meta-analysis of studies reporting on the association between antidepressant use during pregnancy and various pregnancy and delivery outcomes, including spontaneous abortion, gestational age, preterm delivery, birth weight, and Apgar scores.

A Balanced Approach: Weighing Risks and Benefits

This research, like a camel caravan cautiously traversing a desert landscape, navigates the complex terrain of antidepressant use during pregnancy. The authors found no significant association between antidepressant exposure and spontaneous abortion. However, they did identify significant associations between antidepressant exposure and shorter gestational age, preterm delivery, and lower birth weight. The study highlights the importance of carefully considering the risks and benefits of antidepressant use during pregnancy, recognizing that untreated maternal depression can also pose significant risks to both mother and child.

A Delicate Balance: Maternal Well-being and Fetal Health

This research, like a skilled doctor balancing a delicate medical scale, emphasizes the importance of balancing maternal well-being and fetal health. The study reveals that while antidepressant exposure during pregnancy may be associated with some potential risks, the lack of treatment for maternal depression could lead to even more significant adverse outcomes for both mother and child. The findings underscore the importance of individualized treatment plans that consider the specific circumstances of each patient.

Dr.Camel's Conclusion

The decision to use antidepressant medication during pregnancy is a delicate balance, like navigating a narrow desert path. This research provides valuable insights into the potential risks and benefits of antidepressant exposure, highlighting the importance of a careful consideration of individual circumstances. The study emphasizes that the decision to use antidepressants during pregnancy should be made in consultation with a healthcare professional, considering the potential risks and benefits for both mother and child.

Date :
  1. Date Completed 2013-05-31
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

23446732

DOI: Digital Object Identifier

10.1001/jamapsychiatry.2013.684

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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