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Effects of 24-week add-on treatment with ciclesonide and montelukast on small airways inflammation in asthma.

Author: InoueHideki, ItoIsao, IwataToshiyuki, KanemitsuYoshihiro, MatsumotoHisako, MishimaMichiaki, NagasakiTadao, NakajiHitoshi, NiimiAkio, OgumaTsuyoshi, PetrovaGuergana, TajiriTomoko

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Ciclesonide and montelukast add-on therapy to inhaled corticosteroids improved small airway abnormalities and asthma control in patients with stable asthma.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Eosinophilic inflammation of the small airways is a key process in asthma that often smolders in treated patients. The long-term effects of add-on therapy on the persistent inflammation in the small airways remain unknown. OBJECTIVE: To examine the effects of add-on therapy with either ...See full text at original site
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引用元：
https://doi.org/10.1016/j.anai.2012.12.016

データ提供：米国国立医学図書館（NLM）

Addressing Persistent Small Airways Inflammation in Asthma: Exploring Add-on Therapies

Asthma is a chronic respiratory condition that often involves [inflammation of the small airways]. This study investigates the effectiveness of add-on therapies with [ciclesonide] and [montelukast] in reducing small airways inflammation in patients with stable asthma who are already receiving inhaled corticosteroids. The researchers compared the effects of these add-on therapies over a 24-week period, finding that both treatments were beneficial in reducing inflammation and improving asthma control.

Combating Persistent Asthma Inflammation: A Multi-pronged Approach

This research provides valuable insights into the management of asthma, particularly the persistent inflammation that can occur even with standard treatment. The findings suggest that add-on therapies with ciclesonide and montelukast can effectively reduce small airway inflammation and improve asthma control. This research, like a camel caravan navigating a treacherous sandstorm, highlights the importance of a multi-pronged approach to managing this complex condition.

Living with Asthma: Managing Inflammation and Improving Quality of Life

This research offers hope for individuals with asthma, particularly those who continue to experience persistent inflammation despite standard treatment. The effectiveness of ciclesonide and montelukast as add-on therapies provides valuable options for managing this challenge and improving overall quality of life. This research, like a cool oasis in the desert, reminds us that even in the face of ongoing challenges, there are ways to find relief and manage chronic conditions effectively.

Dr.Camel's Conclusion

This research, like a seasoned camel guide leading a caravan through the desert of asthma, highlights the importance of addressing persistent small airway inflammation. It underscores the potential of add-on therapies with ciclesonide and montelukast to improve asthma control and enhance quality of life for individuals living with this chronic condition.

Date :
  1. Date Completed 2013-06-07
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

23548532

DOI: Digital Object Identifier

10.1016/j.anai.2012.12.016

SNS
PICO Info
in preparation
Languages

English

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