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Pharmacokinetic and pharmacodynamic effects of prasugrel in healthy Korean males.
Author: ChoiHyunah C, GuNamyi, KawakatsuEiji, KellyRonan P, ParkKyung Woo, PayneChristopher, PintonPhilippe, SmallDavid S, YuKyung-Sang
Original Abstract of the Article :
Prasugrel is a thienopyridine for treatment of acute coronary syndromes in patients undergoing percutaneous coronary intervention. Higher concentrations of prasugrel's active metabolite (R-138727) have been observed in Asian than white subjects. The primary objective was to investigate pharmacokinet...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1097/FJC.0b013e318290d9e1
データ提供:米国国立医学図書館(NLM)
Prasugrel: A Journey into the World of Thienopyridines
The field of cardiology is a constant pursuit of innovative therapies to combat heart disease. This study delves into the fascinating world of prasugrel, a thienopyridine medication used to treat acute coronary syndromes in patients undergoing percutaneous coronary intervention. Like a camel navigating a challenging desert landscape, researchers seek to understand the intricate workings of this drug and its potential to improve patient outcomes. This study aimed to investigate the pharmacokinetics of prasugrel's active metabolite (R-138727) in healthy Korean males. The authors sought to unveil the unique characteristics of this drug in a specific population, providing valuable insights for clinical practice.
Tailoring Treatment to the Individual
The study's findings suggest that the dosing strategies approved for white patients with acute coronary syndromes may be applicable to Asian patients. However, further research is needed to solidify this conclusion. This highlights the importance of considering individual factors when prescribing medications, recognizing the potential differences in drug metabolism and efficacy across various populations.
Understanding Medication Interactions
This study provides a glimpse into the intricate world of drug interactions. It serves as a reminder that we must consider the unique characteristics of individuals and their responses to medication. Consult with your healthcare professional to ensure that your medication regimen is safe and effective for you.
Dr.Camel's Conclusion
This research underscores the importance of individualized medicine, recognizing that what works for one person may not work for another. It's a journey that involves careful observation, meticulous analysis, and a commitment to tailoring treatment plans to the unique needs of each patient.
Date :
- Date Completed 2013-12-11
- Date Revised 2022-12-07
Further Info :
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