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Long-term maintenance of therapeutic response to lovastatin in patients with familial and non-familial hypercholesterolemia: a 3-year follow-up.
Author: HelveE, KarjalainenK, OjalaJ P, TarkkanenA, TikkanenM J
Original Abstract of the Article :
The 3-year efficacy of lovastatin alone or in combination with colestipol was evaluated in 54 patients with type 2 hyperlipoproteinemia (22 non-familial and 32 familial hypercholesterolemic patients). A sufficient and sustained reduction in LDL cholesterol was achieved in non-familial hypercholester...See full text at original site
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引用元:
https://doi.org/10.1016/0021-9150(90)90147-b
データ提供:米国国立医学図書館(NLM)
Lovastatin for Hypercholesterolemia: A Long-Term Perspective
High cholesterol, like a stubborn desert sand dune, can clog arteries and increase the risk of heart disease. Lovastatin, a statin medication, is a commonly prescribed drug for lowering cholesterol levels.This research evaluates the long-term efficacy and safety of lovastatin in treating familial and non-familial hypercholesterolemia, a condition characterized by high cholesterol levels. The researchers conducted a three-year follow-up study of 54 patients with type 2 hyperlipoproteinemia, a group encompassing both familial and non-familial hypercholesterolemia. Patients were treated with lovastatin alone or in combination with colestipol, another cholesterol-lowering medication.
The study found that lovastatin alone was effective in lowering LDL cholesterol levels in patients with non-familial hypercholesterolemia. However, for patients with familial hypercholesterolemia, a combination therapy with lovastatin and colestipol was required to achieve optimal cholesterol reduction. Both treatment regimens were well-tolerated, with minimal side effects. Importantly, the study did not find any evidence of cataractogenic effects, a potential side effect of statin medications.
Lovastatin: A Long-Term Solution for Managing Cholesterol
This research provides reassuring evidence of the long-term efficacy and safety of lovastatin for treating hypercholesterolemia. It highlights the importance of tailoring treatment regimens based on individual needs and risk factors.Navigating the Desert of Cholesterol: Maintaining a Healthy Heart
The desert of cholesterol management can be challenging, but this research offers valuable insights. It emphasizes the importance of regular monitoring, adherence to treatment regimens, and adopting a healthy lifestyle to maintain optimal cholesterol levels and reduce the risk of heart disease.Dr. Camel's Conclusion
This research highlights the long-term effectiveness and safety of lovastatin in managing hypercholesterolemia, providing reassurance to patients and clinicians alike. It underscores the importance of tailoring treatment strategies to individual needs and the value of maintaining a healthy lifestyle to support cardiovascular health. Just as a camel adapts to the desert's harsh conditions, we must adapt our approach to manage cholesterol levels effectively.Date :
- Date Completed 1990-08-02
- Date Revised 2019-07-18
Further Info :
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