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Cognitive side-effects of antiepileptic drugs in children.

Author: AldenkampAlbert P, IjffDominique M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This article explores the impact of antiepileptic drugs (AEDs) on cognitive function in patients with epilepsy. It highlights the varying cognitive effects of different AEDs, emphasizing the importance of selecting appropriate AEDs to minimize cognitive impairment.
Paper Details　
Original Abstract of the Article :
Although the causes of cognitive impairment in patients with epilepsy have not been completely elucidated, three factors are clearly involved: the underlying etiology of epilepsy, the effects of seizures or the epileptiform EEG discharges themselves, and the central nervous system effects of antiepi...See full text at original site
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引用元：
https://doi.org/10.1016/B978-0-444-52891-9.00073-7

データ提供：米国国立医学図書館（NLM）

Navigating the Cognitive Side Effects of Antiepileptic Drugs in Children

Epilepsy is a neurological disorder that can significantly impact a child's life, particularly their cognitive development. Finding effective treatments for epilepsy while minimizing cognitive side effects is a major challenge for pediatric neurologists. This review explores the cognitive side effects of various antiepileptic drugs (AEDs) commonly used in children. Researchers reviewed available evidence on the impact of different AEDs on cognitive functions, such as attention, memory, and learning, in children. Their findings highlight the need for careful consideration of potential cognitive side effects when selecting AEDs for children with epilepsy.

Understanding the Complexities of AED Use in Children

The review found that certain AEDs, such as phenobarbital and topiramate, are associated with a higher risk of cognitive impairment in children. However, other AEDs, such as levetiracetam and lamotrigine, appear to have less of an impact on cognitive function. This emphasizes the importance of individualizing treatment decisions based on the specific child's needs and the potential risks and benefits of each AED.

Optimizing Treatment Strategies for Children with Epilepsy

The findings of this review highlight the need for careful monitoring and management of cognitive function in children taking AEDs. Regular cognitive assessments and adjustments to medication regimens may be necessary to mitigate potential cognitive side effects. It is crucial to work closely with a qualified healthcare professional to develop the best treatment strategy for each child, ensuring that they receive the most effective epilepsy treatment while minimizing the risk of cognitive impairment.

Dr. Camel's Conclusion

Navigating the cognitive landscape of AEDs for children with epilepsy is like a camel trekking through a shifting desert, searching for the safest and most effective path. While some AEDs may present challenges, others offer a smoother journey. Through careful monitoring and collaboration with healthcare professionals, we can help children with epilepsy thrive, minimizing the impact of their condition on their cognitive development.

Date :
  1. Date Completed 2014-04-01
  2. Date Revised 2013-04-29
Further Info :

Pubmed ID

23622218

DOI: Digital Object Identifier

10.1016/B978-0-444-52891-9.00073-7

SNS
PICO Info
in preparation
Languages

English

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