Anti-inflammatory and anti-oxidant activities of olmesartan medoxomil ameliorate experimental colitis in rats.

Author: ElSayedMoushira I, KhalifaAmani E, NagibMarwa M, TadrosMariane G

Paper Details 
Original Abstract of the Article :
Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) driven through altered immune responses with production of proinflammatory cytokines. Many therapies are used, but side effects and loss of response limit long-term effectiveness. New therapeutic strategies are thus needed for pat...See full text at original site
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引用元:
https://doi.org/10.1016/j.taap.2013.04.026

データ提供:米国国立医学図書館(NLM)

Olmesartan Medoxomil for Ulcerative Colitis: A Potential Oasis in the Desert

Ulcerative colitis (UC), a chronic inflammatory bowel disease, can be a challenging condition to manage. This study, like a camel seeking a haven in the desert, investigates the potential therapeutic effects of olmesartan medoxomil (OLM-M), an angiotensin II receptor blocker, in treating UC.

An Oasis of Relief in the Desert of UC

The study's findings suggest that OLM-M may be effective in ameliorating UC symptoms, potentially offering a new treatment option for individuals with this debilitating condition. OLM-M's ability to reduce inflammation and oxidative stress in the colon suggests its potential as a valuable tool for managing UC.

Navigating the Desert of UC Management

This research highlights the need for exploring novel therapeutic strategies for UC. It underscores the importance of considering the role of angiotensin II and its receptors in the pathogenesis of UC. Just as a camel adapts to the arid desert environment, we must continue to seek new ways to manage UC and improve the quality of life for individuals with this condition.

Dr. Camel's Conclusion

This study, like a rare oasis in the vast desert of UC treatment, offers a potential new pathway to managing this challenging condition. The findings suggest that OLM-M could offer relief for patients struggling with UC. By continuing our exploration of new therapeutic options, we can create a brighter future for individuals facing the challenges of inflammatory bowel diseases. Just as a camel finds sustenance in the desert, we can find hope and healing through continued research and innovation.

Date :
  1. Date Completed 2013-09-16
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

23665423

DOI: Digital Object Identifier

10.1016/j.taap.2013.04.026

Related Literature

SNS
PICO Info
in preparation
Languages

English

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