Fluoxetine increases suicide ideation less than placebo during treatment of adults with minor depressive disorder.

Author: FrankEllen, GarlowSteven J, JuddLewis L, KinkeadBecky, KupferDavid J, RapaportMark Hyman, RushA John, SchettlerPamela J, ThaseMichael E, YonkersKimberly A

Paper Details 
Original Abstract of the Article :
OBJECTIVE: Some reports suggest an increase in suicide ideations and behaviors in patients treated with antidepressants. This is an analysis of the impact of fluoxetine on suicide ideations in outpatients with minor depressive disorder. METHODS: Research subjects were adult outpatients with minor d...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/23786912

データ提供:米国国立医学図書館(NLM)

Fluoxetine and Suicide Ideation: Navigating a Desert of Mental Health

Mental health is a complex and delicate landscape, like a vast desert with hidden dangers. The use of antidepressants has been a subject of ongoing research and debate, with concerns raised about their potential impact on suicide ideation. This study investigated the effects of fluoxetine, a commonly prescribed antidepressant, on suicide ideation in adults with minor depressive disorder. The authors conducted a 12-week, double-blind, randomized trial comparing fluoxetine to placebo.

Fluoxetine: A Safe Oasis in the Desert of Depression?

The study found that fluoxetine was not associated with a clinically significant increase in suicide ideation compared to placebo. Furthermore, survival analysis indicated that patients receiving placebo were more likely to experience an increase in suicide ideation throughout the 12-week trial. The study involved 162 adult outpatients with minor depressive disorder.

A Camel's Perspective on Mental Health

This research provides valuable insights into the safety and effectiveness of fluoxetine for treating minor depressive disorder. It's important to understand that mental health is a complex area, and each individual's experience is unique. This study offers reassurance that fluoxetine, in this particular context, does not appear to increase suicide ideation.

Dr.Camel's Conclusion

This study highlights the complex relationship between antidepressants and suicide ideation. The authors found that fluoxetine, in the context of minor depressive disorder, was not associated with an increase in suicide ideation compared to placebo. It's a reminder that the journey through mental health can be challenging and that responsible and individualized treatment is essential. Like a traveler navigating a desert, seeking the right resources and support is crucial for well-being.

Date :
  1. Date Completed 2014-02-14
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23786912

DOI: Digital Object Identifier

NIHMS490772

Related Literature

SNS
PICO Info
in preparation
Languages

English

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