A pharmacologic approach to the use of glyburide in pregnancy.

Author: CaritisSteve N, HebertMary F

Paper Details 
Original Abstract of the Article :
Despite widespread use of glyburide to treat pregnancy-related hyperglycemia, the dosing regimen is based in large part on pharmacokinetic and pharmacodynamic studies in men and nonpregnant women. Like many medications used by pregnant women, adequate pharmacokinetic and pharmacodynamic data in preg...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/23812467

データ提供:米国国立医学図書館(NLM)

Glyburide: A Pharmacological Oasis for Pregnancy-Related Hyperglycemia

Dr. Camel here, navigating the delicate terrain of pregnancy, a journey through a fertile desert of hormonal changes. Pregnancy-related hyperglycemia, like a heatwave in the desert, can pose challenges for both mother and baby. This research, like a wise desert guide, examines the use of glyburide, a medication commonly used to manage this condition. The researchers, like careful cartographers, explore the pharmacological aspects of glyburide during pregnancy, aiming to optimize its use for safe and effective treatment.

Glyburide: A Dose of Desert Wisdom

The researchers suggest that adjusting the timing of glyburide administration could enhance its efficacy. It's like finding the optimal time to cross a desert, utilizing the cooler hours to minimize the risk of dehydration. Taking glyburide 1 hour before a meal could improve its ability to manage blood sugar levels during pregnancy. This study sheds light on the crucial importance of tailoring medication administration to individual needs, ensuring the best possible outcomes for both mother and baby.

Navigating the Desert of Pregnancy

These findings offer a valuable roadmap for navigating the complex landscape of pregnancy-related hyperglycemia. By adjusting glyburide administration, like finding the right path through a desert, we can help ensure the health and well-being of both mother and baby. This study underscores the importance of carefully considering individual factors when prescribing medications during pregnancy, ensuring a safe and healthy journey through this crucial period.

Dr. Camel's Conclusion

This research is a valuable contribution to the field of pregnancy-related hyperglycemia. It's like discovering a hidden oasis in the vast desert of pregnancy complications, offering a source of relief and improved outcomes for both mother and baby. The researchers have provided valuable insights into the optimal use of glyburide, enhancing our ability to care for pregnant women facing this challenge.

Date :
  1. Date Completed 2013-09-17
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

23812467

DOI: Digital Object Identifier

NIHMS927679

Related Literature

SNS
PICO Info
in preparation
Languages

English

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