Paper Details
- Home
- Paper Details
Immunogenicity and safety of hepatitis E vaccine in healthy hepatitis B surface antigen positive adults.
Author: AiXing, DuHai-Lian, GuoMeng, HuangShou-Jie, JiangHan-Min, LiuXiao-Hui, NgMun-Hon, WangZhong-Ze, WuTing, XiaNing-Shao, YanQiang, YangChang-Lin, ZhangJun, ZhangXue-Feng, ZhuFeng-Cai
Original Abstract of the Article :
A recombinant hepatitis E vaccine, Hecolin, has been proven safe and effective in healthy adults. As hepatitis B surface antigen (HBsAg) positive individuals have a higher risk of poor prognosis after super-infection with hepatitis E virus (HEV), the safety and immunogenicity of Hecolin in this popu...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981858/
データ提供:米国国立医学図書館(NLM)
Hepatitis E Vaccine: A Safe and Effective Option for Hepatitis B Surface Antigen Positive Individuals
Hepatitis E virus (HEV) infection can lead to serious health complications, particularly in individuals with pre-existing liver conditions. This study investigated the safety and immunogenicity of a recombinant hepatitis E vaccine, Hecolin, in adults with hepatitis B surface antigen (HBsAg) positivity. The researchers analyzed data from a large clinical trial to assess the vaccine's effectiveness and safety in this high-risk population.
A Safe and Effective Vaccine for a High-Risk Population
The study confirmed the safety and effectiveness of Hecolin in HBsAg positive adults. The researchers found that the vaccine was well-tolerated, with most adverse events being mild and comparable to those observed in the general population. Furthermore, Hecolin induced strong immune responses in HBsAg positive individuals, indicating its potential to protect this population from HEV infection.
Improving Protection Against Hepatitis E
This research provides valuable information for healthcare providers and public health officials. The study demonstrates that Hecolin is a safe and effective vaccine for HBsAg positive individuals, offering a crucial tool for preventing HEV infection in this high-risk population. The findings underscore the importance of expanding access to this vaccine and ensuring that vulnerable individuals receive the necessary protection.
Dr. Camel's Conclusion
Imagine a desert oasis, a haven for weary travelers. Hecolin, like a refreshing spring in this oasis, provides a safe and effective way to protect individuals with HBsAg positivity from the dangers of HEV infection. This research strengthens our efforts to build a healthier world, free from the burden of preventable diseases.
Date :
- Date Completed 2014-12-24
- Date Revised 2021-10-21
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.