Palonosetron for the prevention of chemotherapy-induced nausea and vomiting.

Author: BlazerMarlo, Mori-VogtSherry

Paper Details 
Original Abstract of the Article :
Chemotherapy-induced nausea and vomiting (CINV) remains both a feared side effect of cancer treatment and a focus of many supportive care initiatives/guidelines. The class of medications known as serotonin receptor antagonists (5-HT3RAs) are integral in the prevention of CINV from both moderately an...See full text at original site
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引用元:
https://doi.org/10.1586/14737140.2013.814412

データ提供:米国国立医学図書館(NLM)

Palonosetron: A New Oasis in the Desert of Chemotherapy-Induced Nausea and Vomiting

In the vast desert of cancer treatment research, we are constantly searching for better ways to manage the side effects of chemotherapy. This study, exploring the field of oncology, investigates the potential of palonosetron, a second-generation serotonin receptor antagonist (5-HT3RA), to prevent chemotherapy-induced nausea and vomiting (CINV), a common and often debilitating side effect.

Imagine a desert with a group of individuals undergoing chemotherapy, experiencing the discomfort of CINV like a scorching desert wind. The researchers investigated the effectiveness of palonosetron in preventing this discomfort. They found that palonosetron, a newer medication with a stronger affinity for the 5-HT3 receptor, a key player in controlling nausea and vomiting, was effective in preventing CINV in many patients.

A Promising Remedy: Palonosetron's Potential

This study suggests that palonosetron, a second-generation 5-HT3RA, may offer a promising option for preventing CINV in patients undergoing chemotherapy. Its higher affinity for the 5-HT3 receptor and longer half-life may provide more effective and sustained relief from nausea and vomiting.

Navigating the Desert of Chemotherapy Side Effects: Seeking Relief

Chemotherapy can be a challenging treatment, with many side effects. This study highlights the importance of exploring effective options to manage these side effects, like palonosetron. It's important to discuss these options with a healthcare professional to determine the best course of action.

Dr.Camel's Conclusion

This research underscores the ongoing quest for better treatments to manage the side effects of cancer therapy. Palonosetron, a newer medication, shows promise in preventing CINV, offering hope for a more comfortable chemotherapy experience. Remember, seeking professional guidance is crucial when considering any new treatment options.

Date :
  1. Date Completed 2014-03-27
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

23984894

DOI: Digital Object Identifier

10.1586/14737140.2013.814412

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