Atorvastatin and hormone therapy influence expression of ABCA1, APOA1 and SCARB1 in mononuclear cells from hypercholesterolemic postmenopausal women.

Author: BertolamiMarcelo C, CavalliSelma A, CerdaAlvaro, FaludiAndre A, GenvigirFabiana D V, HirataMario H, HirataRosario D C, IssaMustafa H, RohdeCintia B

Paper Details 
Original Abstract of the Article :
Reverse cholesterol transport (RCT) has been inversely related to atherosclerosis and cardiovascular risk. The influence of menopause in the RCT process is poorly understood and the effects of cholesterol-lowering interventions, including statins and hormone therapy (HT), on genes controlling the RC...See full text at original site
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引用元:
https://doi.org/10.1016/j.jsbmb.2013.08.017

データ提供:米国国立医学図書館(NLM)

Reverse Cholesterol Transport: A Journey Through the Desert of Menopause

The journey through menopause can be a challenging one, with potential health implications. This research explores the interplay of menopause, cholesterol management, and reverse cholesterol transport (RCT), a process that helps remove cholesterol from the body. The study investigates the effects of atorvastatin, a cholesterol-lowering medication, and hormone therapy (HT) on genes involved in RCT in postmenopausal women.

The Crossroads of Menopause, Cholesterol, and Heart Health

The study highlights the importance of understanding the impact of menopause on heart health. It emphasizes the need to explore how cholesterol-lowering interventions, like statins and HT, may influence the RCT process in postmenopausal women. The authors delve into the intricate relationship between these factors, providing a deeper understanding of the potential implications for heart health during menopause.

Navigating the Desert of Menopause: Keeping Heart Health in Mind

The study underscores the importance of personalized care for women during menopause. It highlights the need to consider individual risk factors and the potential impact of interventions like statins and HT on heart health. The research emphasizes the need for ongoing research to better understand the complex interplay of menopause, cholesterol, and heart health, ensuring that women receive the best possible care during this transition.

Dr. Camel's Conclusion

This research journeys into the desert of menopause, exploring the intricate connections between cholesterol, heart health, and the effects of various interventions. The study highlights the importance of addressing the unique needs of women during menopause and underscores the ongoing need for research to ensure that women receive the best possible care during this transition.

Date :
  1. Date Completed 2014-01-08
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

24007717

DOI: Digital Object Identifier

10.1016/j.jsbmb.2013.08.017

Related Literature

SNS
PICO Info
in preparation
Languages

English

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