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Glucose targets in pregnant women with diabetes: a systematic review and meta-analysis.

Author: Carranza LeonBarbara G, DomecqJuan Pablo, ElraiyahTarig, MontoriVictor M, MuradM Hassan, NabhanMohammed, PrutskyGabriela J, SundareshVishnu, VellaAdrian, WangZhen

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

A review of 34 studies found that a fasting glucose target of <90 mg/dL was associated with a lower risk of macrosomia in women with gestational diabetes during the third trimester. However, data were sparse and inconclusive for other glucose targets and for women with pregestational diabetes.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Glucose-lowering treatments are used during pregnancy to reduce the risk for complications in the mother and offspring, yet treatment targets have not been established. OBJECTIVE: Our objective was to appraise and summarize the available evidence regarding the association between differ...See full text at original site
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引用元：
https://doi.org/10.1210/jc.2013-2461

データ提供：米国国立医学図書館（NLM）

Charting a Course for Optimal Glucose Control in Pregnancy

This study delves into the complex landscape of glucose control during pregnancy, examining the association between different blood glucose targets and maternal and fetal outcomes. The researchers conducted a systematic review and meta-analysis, a meticulous approach that involves analyzing data from multiple studies, to synthesize the available evidence. Their findings suggest that a fasting glucose target of less than 90 mg/dL, a critical threshold akin to a landmark in a vast desert, was associated with a reduced risk of macrosomia, a condition characterized by an abnormally large fetus, in women with gestational diabetes during the third trimester. The study underscores the importance of maintaining optimal glucose control during pregnancy to mitigate potential risks for both mother and child.

A Guidepost for Glucose Management in Pregnancy

The study provides valuable insights for managing glucose levels in pregnant women with diabetes. The researchers' findings, based on a comprehensive review of the existing literature, offer a roadmap for setting appropriate glucose targets during pregnancy. This research encourages healthcare professionals to carefully monitor glucose levels and adjust treatment strategies to maintain optimal control, minimizing risks for both mother and child.

A Journey Through the Desert of Pregnancy

This study emphasizes the importance of navigating the complexities of pregnancy with diabetes, particularly the need for personalized glucose management strategies. The researchers' findings highlight the need for a more nuanced approach to setting glucose targets, considering individual factors and potential risks. This research encourages continued exploration of the optimal glucose control strategies during pregnancy to ensure the well-being of both mother and child.

Dr.Camel's Conclusion

This systematic review and meta-analysis provide valuable insights into the association between different blood glucose targets and maternal and fetal outcomes in pregnant women with diabetes. The findings suggest that a fasting glucose target of less than 90 mg/dL during the third trimester may be beneficial for women with gestational diabetes, minimizing the risk of macrosomia. This research encourages a more nuanced approach to managing glucose control during pregnancy, prioritizing individual factors and potential risks.

Date :
  1. Date Completed 2014-01-02
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

24151289

DOI: Digital Object Identifier

10.1210/jc.2013-2461

SNS
PICO Info
in preparation
Languages

English

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