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A randomized, placebo-controlled, double-blind trial of sertraline for postpartum depression.

Author: CzarkowskiKathryn A, EppersonC Neill, GueorguievaRalitza, HantsooLiisa, PriceLawrence H, Ward-O'BrienDeborah

Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A randomized double-blind placebo-controlled trial of sertraline for treating postpartum depression found that sertraline produced a significantly greater response rate and a higher remission rate compared to placebo. These findings suggest that sertraline could be an effective treatment for postpartum depression, especially in women with onset of depression within 4 weeks of childbirth.
Paper Details　
Original Abstract of the Article :
RATIONALE: Postpartum depression (PMD) occurs in roughly 10 % of postpartum women and negatively impacts the mother and her offspring, but there are few placebo-controlled studies of antidepressant treatment in this population. OBJECTIVE: The objective was this study is to compare the selective ser...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/24173623

データ提供：米国国立医学図書館（NLM）

Sertraline for Postpartum Depression: A Beacon of Hope

The desert of [postpartum depression (PMD)] can be a lonely and isolating place. This research explored the effectiveness of [sertraline] in treating PMD, finding that it was [significantly more effective] than [placebo] in [achieving response and remission]. The study included [38 women] who experienced [depression onset within 3 months of delivery] and found that sertraline led to [higher rates of response and remission] compared to placebo. The findings suggest that sertraline may be a [valuable treatment option] for women experiencing PMD.

Sertraline Shows Promise for Postpartum Depression

The research offers encouraging evidence for the use of [sertraline] in treating PMD. The study suggests that this medication could effectively [reduce symptoms of depression] and potentially [improve outcomes] for many women experiencing this challenging condition.

Finding Support and Seeking Help

This research underscores the importance of [seeking professional help] if you are experiencing PMD. It highlights the availability of [effective treatments] and the potential for [significant improvement]. Don't hesitate to [reach out to your healthcare provider] for support and guidance in managing this condition.

Dr. Camel's Conclusion

This research, like a gentle oasis in the midst of a harsh desert, offers hope and support for women experiencing postpartum depression. The findings highlight the potential of sertraline as an effective treatment, encouraging women to seek help and support in managing this challenging condition.

Date :
  1. Date Completed 2015-02-19
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

24173623

DOI: Digital Object Identifier

NIHMS536580

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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