Paper Details

  1. Home
  2. Paper Details

Evaluating the side effects of treatment for preterm labor in a center that uses "high-dose" magnesium sulfate.

Author: Bodea-BraescuAna V, EdwardsRodney K, IngersollMelissa, MeschterErin, WilsonMatthew S

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A high dose of intravenous magnesium sulfate used for tocolysis was found to cause side effects in 9 out of 10 patients, with severe side effects occurring in 1 out of 20. These side effects included pulmonary edema, respiratory arrest, intensive care unit transfer, cardiac arrest, or death. Severe side effects were more common in patients with multifetal gestations, those receiving larger doses of magnesium, or those receiving multiple tocolytics.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To evaluate the tolerability and safety of intravenous magnesium sulfate use for tocolysis in a center that uses a "high-dose" regimen. STUDY DESIGN: We conducted a retrospective cohort study of patients treated with magnesium sulfate for preterm labor from December 2006 to June 2010. Da...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1055/s-0033-1358770

データ提供：米国国立医学図書館（NLM）

Evaluating the Side Effects of Magnesium Sulfate for Preterm Labor

This research explores the safety and tolerability of magnesium sulfate, a medication commonly used to prevent preterm labor. The study investigates the side effects of a high-dose regimen of magnesium sulfate in a group of pregnant women who were experiencing preterm labor. The researchers analyzed patient data to evaluate the incidence and severity of side effects associated with this treatment.

High-Dose Magnesium Sulfate: Significant Side Effects

The study found that high-dose magnesium sulfate is associated with a high incidence of side effects, affecting 9 out of 10 patients. While most side effects are mild, severe complications, such as pulmonary edema, occur in 1 out of 20 patients. The study also discovered that multiple pregnancies and the use of multiple tocolytics increase the risk of severe side effects.

A Cautious Approach to Magnesium Sulfate

This study underscores the importance of carefully weighing the risks and benefits of high-dose magnesium sulfate for preterm labor. It's like carefully navigating a desert landscape, where a wrong step can lead to unexpected consequences. This study emphasizes the need for caution in managing preterm labor, especially in women with multiple pregnancies.

Dr.Camel's Conclusion

This research highlights the importance of carefully considering the risks and benefits of medications, especially during pregnancy. It's a reminder that we must always be vigilant and make informed decisions about healthcare.

Date :
  1. Date Completed 2015-04-16
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

24338122

DOI: Digital Object Identifier

10.1055/s-0033-1358770

Related Literature

Article Analysis
・Side Effects of magnesium sulfate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.