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Skin delivery of kojic acid-loaded nanotechnology-based drug delivery systems for the treatment of skin aging.

Author: ChorilliM, CorrêaM A, GonçalezM L

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Kojic acid (KA) is a traditional skin-lightening agent used to treat skin aging and hyperpigmentation. This study developed a liquid crystalline system (LCS) for KA delivery to improve skin penetration and retention. Formulations containing KA were characterized, and results showed that the LCS modulated KA permeation through the skin, with minimal cytotoxicity. These results suggest that PPG-5-CETETH-20-based LCSs may be a promising platform for KA skin delivery.
Paper Details　
Original Abstract of the Article :
The aging process causes a number of changes in the skin, including oxidative stress and dyschromia. The kojic acid (KA) is iron chelator employed in treatment of skin aging, and inhibits tyrosinase, promotes depigmentation. Nanotechnology-based drug delivery systems, such as liquid crystalline syst...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867863/

データ提供：米国国立医学図書館（NLM）

Kojic Acid: A Desert Wanderer Seeking Youthful Skin

The quest for youthful skin is a journey that has fascinated humankind for centuries. This research explores the potential of [kojic acid] as a [skin-aging treatment], utilizing [nanotechnology-based drug delivery systems] to enhance its effectiveness. The study examines the development and characterization of kojic acid-loaded liquid crystalline systems, evaluating their in vitro skin permeation and retention properties.

Kojic Acid: A Potential Fountain of Youth in the Desert of Aging

The research suggests that kojic acid-loaded liquid crystalline systems may offer a promising approach to delivering this active ingredient to the skin, potentially contributing to a more youthful appearance. It’s like finding a hidden spring of youth in the vast and unforgiving desert of aging.

Kojic Acid: A New Frontier in Skincare

This research highlights the potential of nanotechnology-based drug delivery systems to enhance the effectiveness of skincare ingredients, offering a promising avenue for future developments in the field. It’s a reminder that the desert of skincare innovation is constantly expanding, offering new avenues for achieving youthful and radiant skin.

Dr.Camel's Conclusion

This research offers a glimpse into the potential of kojic acid-loaded liquid crystalline systems as a novel approach to skincare, offering a potential oasis in the quest for youthful radiance.

Date :
  1. Date Completed 2014-07-29
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24369010

DOI: Digital Object Identifier

PMC3867863

Related Literature

Article Analysis
・Effective treatment of skin aging
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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