Treatment of capecitabine-induced hand-foot syndrome using a topical retinoid: A case report.

Author: FujimuraTakashi, FurukawaHiroyuki, FushidaSachio, InokuchiMasafumi, IshikawaSatoko, KitagawaHirohisa, NinomiyaItasu, OhtaTetsuo, TakamuraHiroyuki

Paper Details 
Original Abstract of the Article :
Capecitabine is a chemotherapeutic drug used in patients with breast, colon and gastric cancer. Hand-foot syndrome (HFS) is a type of dermatitis that frequently occurs as a reaction to capecitabine. To date, no effective strategies have been found to prevent or reverse HFS. Furthermore, chemotherapy...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881915/

データ提供:米国国立医学図書館(NLM)

Treating Capecitabine-Induced Hand-Foot Syndrome

Imagine [capecitabine] as a powerful weapon against cancer, but like a double-edged sword, it can also cause side effects. [Hand-foot syndrome (HFS)] is a common side effect of capecitabine, characterized by painful inflammation of the hands and feet, like walking barefoot on scorching sand. This study explored the potential of [topical retinoids], like a soothing balm, to alleviate HFS and potentially enhance the effectiveness of chemotherapy.

Topical Retinoids: A Promising Avenue

The study presents a case report of a patient with refractory HFS effectively treated with [topical adapalene], offering hope for a less painful journey for those undergoing capecitabine therapy. It's like finding a hidden spring in the desert, offering respite from the heat and dryness.

Future Research Directions

While this study suggests the potential of topical retinoids in treating HFS, further research is needed to confirm their effectiveness and to understand their mechanism of action. It's like exploring a new oasis in the desert, carefully studying its properties and resources.

Dr. Camel's Conclusion

This case report offers a glimmer of hope for managing capecitabine-induced hand-foot syndrome. It's like finding a shady spot under a desert palm tree, providing temporary relief from the harsh sun. Further research is needed to validate this promising approach and to bring comfort to those experiencing this debilitating side effect.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24396465

DOI: Digital Object Identifier

PMC3881915

Related Literature

SNS
PICO Info
in preparation
Languages

English

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