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Combination varenicline and bupropion SR for tobacco-dependence treatment in cigarette smokers: a randomized trial.
Author: AllenSharon S, CroghanIvana T, EbbertJon O, HatsukamiDorothy K, HaysJ Taylor, HurtRichard D, SchroederDarrell R
Original Abstract of the Article :
IMPORTANCE: Combining pharmacotherapies for tobacco-dependence treatment may increase smoking abstinence. OBJECTIVE: To determine efficacy and safety of varenicline and bupropion sustained-release (SR; combination therapy) compared with varenicline (monotherapy) in cigarette smokers. DESIGN, SETTI...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/24399554
データ提供:米国国立医学図書館(NLM)
Combining Varenicline and Bupropion for Smoking Cessation
The battle against [tobacco dependence] is a long and arduous journey, like navigating a vast and unforgiving desert. This study, like a seasoned explorer seeking a hidden oasis of relief, investigates the potential benefits of combining two pharmacotherapies, [varenicline] and [bupropion], for smoking cessation. The researchers sought to determine if this combination therapy could improve smoking abstinence rates compared to [varenicline monotherapy].
Combination Therapy Shows Promise for Smoking Cessation
The study revealed that [combination therapy] significantly increased [prolonged abstinence] rates compared to [varenicline monotherapy] at [12 and 26 weeks]. This finding is like discovering a hidden spring in the desert, providing a much-needed source of relief for those struggling to quit smoking. However, the researchers also noted that the combination therapy was associated with a slightly higher risk of [anxiety] and [depressive symptoms].
Weighing the Benefits and Risks of Combination Therapy
The study suggests that [combination therapy] may be a promising option for smokers seeking to quit, but it is essential to carefully weigh the potential benefits and risks. As with any desert oasis, there may be hidden dangers, so it is important to consult with a healthcare professional to determine if combination therapy is right for you.
Dr.Camel's Conclusion
This study provides encouraging evidence for the potential of combining varenicline and bupropion for smoking cessation, but it also highlights the importance of careful monitoring for potential side effects. Like a desert oasis, combination therapy can offer much-needed relief, but it's essential to be mindful of its unique characteristics and navigate it with caution.
Date :
- Date Completed 2014-01-13
- Date Revised 2022-03-16
Further Info :
Related Literature
English
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