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Excluding the typical patient: thirty years of pharmacotherapy efficacy trials for obsessive-compulsive disorder.
Author: EisenJane L, GrantJon E, ManceboMaria C, MortensenErik L, OdlaugBrian L, RasmussenSteven A, SchreiberLiana R N, WeinhandlEric
Original Abstract of the Article :
Over the past 30 years, clinical trials have resulted in several successful pharmacotherapies for obsessive-compulsive disorder (OCD), yet patients in clinical settings often report inadequate response. This study compares clinical characteristics of treatment-seeking OCD patients to the inclusion/e...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/24501729
データ提供:米国国立医学図書館(NLM)
OCD Treatment: Bridging the Gap Between Research and Reality
My esteemed colleagues, we enter the world of obsessive-compulsive disorder (OCD), a complex mental health condition characterized by intrusive thoughts and repetitive behaviors. This study, much like a seasoned traveler navigating the vast desert of mental health research, examines the discrepancy between the effectiveness of pharmacotherapies for OCD in clinical trials and the often-reported inadequate response in real-world settings.
The researchers, published in [journal name], compared the characteristics of OCD patients seeking treatment in clinical settings to the inclusion and exclusion criteria used in pharmacotherapy trials. Their analysis reveals that many patients seeking treatment in real-world settings do not meet the strict criteria for participation in clinical trials. This mismatch, much like a desert mirage, can create a disconnect between research findings and clinical practice.
The researchers highlight the importance of addressing the limitations of clinical trials in representing the diversity of OCD patients in real-world settings. They suggest that future research should focus on developing more inclusive criteria and exploring alternative treatment approaches for those who do not respond well to traditional pharmacotherapies.
The Importance of Inclusive Research
This study, like a compass guiding us through the complexities of mental health research, underscores the need for more inclusive and representative clinical trials. By broadening the scope of research to include a wider range of patients, we can gain a more comprehensive understanding of OCD and develop more effective treatments.
Implications for OCD Treatment
This research has significant implications for the treatment of OCD. It highlights the importance of considering individual patient characteristics and exploring alternative treatment approaches when traditional pharmacotherapies fail. It’s a reminder that the desert of mental health research is vast and requires ongoing exploration to develop personalized and effective treatments for all.
Dr. Camel's Conclusion
This study, like a lone traveler discovering a hidden path in the desert, reveals the gap between research findings and real-world clinical practice in the treatment of OCD. The researchers emphasize the need for more inclusive research to develop better treatments for this complex condition. It’s a reminder that the journey to improving mental health requires constant vigilance and a commitment to exploring new avenues and perspectives.
Date :
- Date Completed 2014-10-26
- Date Revised 2021-10-21
Further Info :
Related Literature
English
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