Delayed/non-union of upper limb fractures with bisphosphonates: systematic review and recommendations.

Author: JosephSamuel, NgAndrew Jin-Hean, RichardsonMartin, YueBrian

Paper Details 
Original Abstract of the Article :
Bisphosphonates (BPs) are widely used for the treatment of osteoporosis. Oversuppression of bone turnover with BPs may paradoxically limit the reserve capacity of bone to heal. The aim of this review was to study the predisposition of some patients to delayed/non-union of upper limb fractures associ...See full text at original site
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引用元:
https://doi.org/10.1111/ans.12536

データ提供:米国国立医学図書館(NLM)

Bisphosphonates: A Double-Edged Sword in Fracture Healing

This study examines the complex relationship between bisphosphonates (BPs), commonly used to treat osteoporosis, and the healing of upper limb fractures. While BPs are known for their bone-strengthening effects, they can also paradoxically suppress bone turnover, potentially hindering the body's ability to heal fractures. The researchers conducted a systematic review to investigate the association between BPs and delayed or non-union fractures in upper limbs. This research aims to shed light on the potential complications of BPs in fracture management and provide recommendations for optimal treatment strategies.

Bisphosphonates: A Balancing Act for Fracture Healing

The review highlights the potential for BPs to interfere with fracture healing, underscoring the importance of careful consideration when managing patients on these medications. The researchers emphasize the need for a delicate balance between the benefits of BPs in preventing osteoporosis and their potential to impede fracture healing. This research provides valuable guidance for clinicians in optimizing fracture management strategies for patients receiving BPs.

Navigating the Desert of Fracture Healing

Think of the desert as a landscape where fractures represent canyons and BPs act as shifting sands that can both stabilize and hinder the healing process. This research serves as a compass, guiding us through the complexities of fracture management in patients receiving BPs, ensuring we navigate the desert of bone healing with caution and precision.

Dr.Camel's Conclusion

This research sheds light on the intricate relationship between bisphosphonates and fracture healing, emphasizing the need for a balanced approach. Just as a desert landscape can be both treacherous and beautiful, understanding the potential benefits and drawbacks of bisphosphonates is crucial for optimal fracture care. This study reminds us that even in the vast desert of medical knowledge, continuous exploration and adaptation are key to providing the best possible care.

Date :
  1. Date Completed 2014-12-01
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

24529100

DOI: Digital Object Identifier

10.1111/ans.12536

Related Literature

SNS
PICO Info
in preparation
Languages

English

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