Paper Details 
Original Abstract of the Article :
We studied whether the Etest can be used as an alternative to agar dilution to determine antimicrobial susceptibilities of ceftriaxone, cefixime, and cefpodoxime in Neisseria gonorrhoeae surveillance. One hundred fifteen clinical and laboratory isolates of N. gonorrhoeae were tested following the Cl...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993651/

データ提供:米国国立医学図書館(NLM)

Etest: A New Oasis in the Desert of Antimicrobial Susceptibility Testing

Neisseria gonorrhoeae, a bacterium responsible for gonorrhea, poses a significant public health challenge due to its increasing resistance to antibiotics. This study investigates the potential of Etest, a rapid and convenient method for determining antimicrobial susceptibility, as an alternative to the traditional agar dilution method.

The researchers compared the results of Etest and agar dilution testing for 115 clinical and laboratory isolates of N. gonorrhoeae, evaluating the susceptibility of these isolates to ceftriaxone, cefixime, and cefpodoxime. They found a strong correlation between the two methods, with high levels of agreement within one or two log2 dilutions.

The study concludes that Etest can be effectively used as an alternative to agar dilution testing for determining the susceptibility of N. gonorrhoeae to these antibiotics. However, the researchers recommend further research into extremely resistant isolates and suggest that reexamination of the Etest interpretation may be necessary to ensure accurate categorization of susceptible and nonsusceptible isolates.

A New Path in Antimicrobial Susceptibility Testing

The study demonstrates the potential of Etest as a viable alternative to agar dilution testing for determining antimicrobial susceptibility of N. gonorrhoeae. This research highlights the importance of developing efficient and reliable methods for antimicrobial susceptibility testing, especially in the face of increasing antibiotic resistance.

A New Path in Antimicrobial Susceptibility Testing

The fight against antibiotic resistance is a constant battle. This research emphasizes the need for ongoing research and development of new and improved methods for antimicrobial susceptibility testing. Just as a camel needs to adapt to the changing desert landscape, we must be vigilant in our efforts to combat antibiotic resistance and safeguard public health.

Dr.Camel's Conclusion

This study explores the potential of Etest as a rapid and convenient alternative to agar dilution testing for determining antimicrobial susceptibility of Neisseria gonorrhoeae. While further research is needed, the findings offer a promising new tool for combating antibiotic resistance and ensuring effective treatment of gonorrhea.

Date :
  1. Date Completed 2015-02-24
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

24554750

DOI: Digital Object Identifier

PMC3993651

Related Literature

SNS
PICO Info
in preparation
Languages

English

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