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Granisetron transdermal system improves refractory nausea and vomiting in gastroparesis.

Author: ParkmanHenry P, SimmonsKellie

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Granisetron transdermal patch was moderately effective in reducing refractory symptoms of nausea and/or vomiting from gastroparesis in 50% of patients.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Symptoms of gastroparesis include nausea and vomiting, which can markedly diminish quality of life. Nausea and vomiting can also make treatment with oral antiemetics problematic. AIM: Our aim was to determine whether treatment-resistant nausea and vomiting in patients with gastroparesis...See full text at original site
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引用元：
https://doi.org/10.1007/s10620-014-3097-3

データ提供：米国国立医学図書館（NLM）

Granisetron Transdermal System Improves Refractory Nausea and Vomiting in Gastroparesis

The management of [gastroparesis], a condition characterized by delayed gastric emptying, can be challenging due to persistent [nausea and vomiting]. This pilot study investigated the effectiveness of [granisetron transdermal patch (GTP)] in treating [refractory nausea and vomiting] in patients with gastroparesis. The study found that [GTP was moderately effective] in reducing symptoms in approximately [50%] of patients.

GTP as a Potential Treatment for Gastroparesis

The pilot study suggests that [GTP] may be a valuable treatment option for patients with [gastroparesis] who experience [refractory nausea and vomiting]. The study observed a [moderate improvement] in symptoms for a significant portion of participants.

Finding Relief from Gastroparesis Symptoms

For individuals dealing with the discomfort of [gastroparesis], this study offers a glimmer of hope. While [GTP] is not a guaranteed solution, it demonstrates potential for [alleviating symptoms] in some patients. This underscores the importance of [exploring different treatment options] in consultation with a healthcare professional to find the best approach for managing gastroparesis.

Dr.Camel's Conclusion

Just as a camel can endure the harsh desert heat, patients with gastroparesis can find relief from their symptoms. This study highlights the potential of [GTP] as a treatment option, offering a ray of hope to individuals struggling with this condition. It's important to remember that [every patient is unique] and finding the right treatment requires collaboration between patient and healthcare provider.

Date :
  1. Date Completed 2014-07-15
  2. Date Revised 2022-03-09
Further Info :

Pubmed ID

24615549

DOI: Digital Object Identifier

10.1007/s10620-014-3097-3

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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