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Cerebellar and oculomotor dysfunction induced by rapid infusion of pethidine.
Author: ChuPo-Wei, DaiYang-Hong, OuKuang-Ling
Original Abstract of the Article :
Pethidine is an opioid that gains its popularity for the effective pain control through acting on the opioid-receptors. However, rapid pain relief sometimes brings about unfavourable side effects that largely limit its clinical utility. Common side effects include nausea, vomiting and hypotension. I...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962981/
データ提供:米国国立医学図書館(NLM)
Pethidine's Inhibitory Effects on Cerebellar and Oculomotor Function
Pethidine, a commonly used opioid, is like a double-edged sword in the desert of pain management. It effectively relieves pain but can also cause unwanted side effects. This case report investigates the inhibitory impacts of pethidine on the central nervous system (CNS), particularly on the cerebellum and oculomotor function.
The report highlights the potential for rapid pethidine infusion to induce cerebellar and oculomotor dysfunction, characterized by dysmetria, dysarthria, reduced smooth pursuit gain, and decreased saccadic velocity. These effects are like a sandstorm disrupting the delicate balance of a desert ecosystem.
Understanding the Side Effects of Pethidine
This case report sheds light on a less commonly discussed side effect of pethidine. It's like discovering a hidden canyon in the vast desert, revealing a new aspect of the landscape. This study underscores the importance of understanding the potential complications associated with pethidine, especially in patients with impaired renal or liver function or those requiring long-term pain management.
Cautious Approach to Pethidine Use
This report emphasizes the need for careful consideration when administering pethidine, especially in patients with pre-existing conditions. Just like navigating a desert, it's essential to be aware of potential pitfalls and adjust your path accordingly. Clinicians must weigh the benefits of pethidine against the potential risks, particularly for those with compromised renal or liver function.
Dr.Camel's Conclusion
This case report highlights the potential for pethidine to induce cerebellar and oculomotor dysfunction, highlighting the importance of understanding the full range of its effects. Like a wise camel navigating the desert, clinicians must be aware of the potential complexities of this widely used opioid.
Date :
- Date Completed 2014-10-22
- Date Revised 2021-10-21
Further Info :
Related Literature
English
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