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Cardiovascular effects of phentermine and topiramate: a new drug combination for the treatment of obesity.

Author: AstrupArne, DayWesley W, EngeliStefan, FinerNick, JordanJens, NarkiewiczKrzysztof

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Phentermine and topiramate are used for weight loss, individually and in combination. Long-term use of this combination may be a safe and effective option for reducing weight in overweight/obese patients at low-to-intermediate cardiovascular risk.
Paper Details　
Original Abstract of the Article :
Weight loss can reduce the increased cardiovascular risk associated with obesity. Pharmacotherapy is a recognized weight loss treatment option; however, cardiovascular safety issues with some previous weight loss drugs raise concerns for newly approved pharmacotherapies. Phentermine is approved for ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011567/

データ提供：米国国立医学図書館（NLM）

Phentermine and Topiramate: A New Hope for Obesity Treatment

Obesity is a major health concern worldwide, and the search for safe and effective weight loss treatments continues. This study delves into the cardiovascular risks and benefits of a combination therapy using phentermine and topiramate extended-release.

A Safer Option for Weight Management

The researchers reviewed data on the long-term use of this combination therapy and found that it may be a safe and effective option for reducing weight in overweight/obese patients at low-to-intermediate cardiovascular risk.

Balancing Weight Loss with Cardiovascular Health

This study reminds us of the importance of finding a balance between weight management and cardiovascular health. If you're considering weight loss medications, it's crucial to discuss your individual risks and benefits with your doctor. Just like a camel adapts to survive in the desert, finding the right approach for your health journey is key.

Dr.Camel's Conclusion

This research provides encouraging evidence for the potential of this drug combination in treating obesity, especially in patients with lower cardiovascular risk. Further research is needed to understand the long-term effects of this combination therapy, but it offers a ray of hope in the ongoing fight against obesity.
Date :
  1. Date Completed 2015-02-19
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

24621808

DOI: Digital Object Identifier

PMC4011567

Related Literature

Article Analysis
・Effects of phentermine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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