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Short-term treatment with parecoxib for complex regional pain syndrome: a randomized, placebo-controlled double-blind trial.

Author: BreuerAnna J, HanselNora, KrumovaElena K, MaierChristoph, MainkaTina

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Complex regional pain syndrome (CRPS) is characterized by inflammation and heightened sensitivity to pain in the affected area. This study aims to see if a medication that blocks a specific type of inflammation (COX-2 inhibitor) can reduce pain sensitivity, pain intensity, and swelling in people with CRPS.
Paper Details　
Original Abstract of the Article :
Complex regional pain syndrome (CRPS) is characterized by signs and symptoms of peripheral inflammation, which leads to peripheral neural sensitization associated most frequently (in about 70%) with blunt pressure hyperalgesia. Therefore, we hypothesized that treatment of CRPS patients with a select...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/24658473

データ提供：米国国立医学図書館（NLM）

A New Oasis in the Desert of Complex Regional Pain Syndrome

[Complex regional pain syndrome (CRPS)] is a debilitating condition characterized by chronic pain and inflammation. This study investigates the potential of [parecoxib], a [selective COX-2-inhibitor], to alleviate the symptoms of [CRPS]. It is like searching for a new oasis in the desert of [pain management], seeking out a more effective way to treat this chronic condition. The study found that [short-term treatment with parecoxib] improved [pressure pain threshold] and reduced [pain intensity] and [edema] in patients with [CRPS]. This suggests that [parecoxib] may be a valuable tool for managing the symptoms of this difficult condition.

Parecoxib's Potential for CRPS Treatment

The results of this study are encouraging for patients with [CRPS]. The findings suggest that [parecoxib] may be a valuable tool for managing the pain and inflammation associated with this condition.

Hope for a More Comfortable Life

The findings of this study offer hope for patients with [CRPS]. The potential of [parecoxib] to alleviate [pain intensity] and [edema] offers a glimmer of hope for a more comfortable life.

Dr.Camel's Conclusion

The desert of [CRPS] is a harsh landscape, but this study provides a potential oasis in the form of [parecoxib]. The findings suggest that this medication may be a valuable tool for managing the symptoms of this debilitating condition, offering a glimmer of hope for a more comfortable life.

Date :
  1. Date Completed 2014-11-17
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

24658473

DOI: Digital Object Identifier

24658473

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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