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Double-blind, placebo-controlled, crossover study of early-intervention with sumatriptan 85/naproxen sodium 500 in (truly) episodic migraine: what's neck pain got to do with it?

Author: CalhounAnne H, FordSutapa

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

While triptans are used to treat migraine headaches, studies have shown limited effectiveness, with only 18-58% of people becoming pain-free after two hours. This study aims to see if sumatriptan and naproxen are more effective in people with truly episodic migraines, meaning they only experience headaches occasionally and not just mild or neck pain.
Paper Details　
Original Abstract of the Article :
Published studies of triptans in acute migraine have shown relatively disappointing 2-hour pain-free rates, ranging from 18% to 58%, with 2- to 24-hour sustained pain-free rates from 17% to 25%. A major flaw in the design of previous studies may have contributed to disappointing results: many subjec...See full text at original site
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引用元：
https://doi.org/10.3810/pgm.2014.03.2743

データ提供：米国国立医学図書館（NLM）

Migraine Relief: A Double-Blind Study of Sumatriptan/Naproxen

This study delves into the effectiveness of sumatriptan/naproxen in treating episodic migraine, a debilitating condition that can cause intense headaches and other debilitating symptoms. It's like exploring a hidden oasis in the desert, seeking a solution for this recurring pain. The researchers recognized a flaw in previous studies, which often included patients who were not truly episodic migraineurs, meaning they experienced headaches on a more frequent basis. The study focused on truly episodic migraineurs, ensuring a more accurate assessment of the drug's effectiveness. The results suggest that early treatment with sumatriptan/naproxen could be a more robust solution for this specific group of patients.

Sumatriptan/Naproxen: A Potential Solution for Episodic Migraine

The study highlighted the importance of including only truly episodic migraineurs in clinical trials to obtain accurate results. This approach, coupled with early treatment using sumatriptan/naproxen, showed promising outcomes for this specific group of patients. This research underscores the need for a tailored approach to migraine treatment, considering the individual characteristics and experiences of patients.

Managing Migraines: A Personalized Approach

This study highlights the importance of accurately diagnosing and treating episodic migraine to ensure effective relief. It emphasizes the need for a tailored approach, considering individual patient characteristics and preferences. Finding the right treatment can be like discovering a hidden oasis in the desert, providing much-needed relief from the pain and discomfort of migraines.

Dr.Camel's Conclusion

This research underscores the need for a personalized approach to migraine treatment, considering the individual characteristics of patients. Early treatment with sumatriptan/naproxen may be a more effective solution for those with truly episodic migraines. It's like finding a hidden oasis in the desert, offering relief from the pain and discomfort of migraines.

Date :
  1. Date Completed 2014-05-19
  2. Date Revised 2014-04-01
Further Info :

Pubmed ID

24685971

DOI: Digital Object Identifier

10.3810/pgm.2014.03.2743

Related Literature

Article Analysis
・Effective treatment of migraine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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