Anthropometric measurements and lipid profiles to detect early lipodystrophy in antiretroviral therapy experienced HIV-infected children in the CHAPAS-3 trial.

Author: , AbongomeraGeorge, ArachBeatrice, AsiimweAlice R, CookAdrian, GibbDiana M, KabambaDesiree, KayiwaJoshua, KekitiinwaAdeodata, KennyJulia, KityoCissy, KleinNigel, KomunyenaJustine, MirembeGrace, MulengaVeronica, MusiimeVictor, NansubugaCarol, WalkerSarah A, WavamunnoPriscilla, ZangataDorothy

Paper Details 
Original Abstract of the Article :
BACKGROUND: Few studies have investigated objective markers of lipodystrophy in African children. We compared body circumferences, skin-fold thickness (SFT) and lipids in antiretroviral therapy (ART)-naive and stavudine (d4T)-exposed children with HIV-uninfected controls. METHODS: In the CHAPAS-3 t...See full text at original site
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引用元:
https://doi.org/10.3851/IMP2695

データ提供:米国国立医学図書館(NLM)

Early Detection of Lipodystrophy: A Desert Oasis in HIV Treatment

The field of [HIV treatment] has made remarkable strides, but managing the long-term effects of [antiretroviral therapy (ART)] remains a critical challenge. This study investigated the potential of [anthropometric measurements] and [lipid profiles] as early indicators of [lipodystrophy] in [HIV-infected children]. The researchers compared these measures in [ART-naive] and [d4T-exposed] children to [HIV-uninfected controls]. Their findings suggest that specific anthropometric and lipid markers can signal the onset of lipodystrophy, allowing for early intervention and potentially mitigating long-term complications.

Early Detection: A Key to Effective Management

The results show that [ART-experienced] children on d4T-containing regimens had lower [skin-fold thickness] and higher [total cholesterol] and [low-density lipoprotein] levels compared to [ART-naive] children and [HIV-uninfected controls]. These findings highlight the importance of regular monitoring for early signs of lipodystrophy in children receiving ART.

Monitoring for Lipodystrophy: A Desert Oasis in HIV Treatment

This research underscores the need for vigilant monitoring of anthropometric and lipid profiles in HIV-infected children on ART. Early detection of lipodystrophy allows for timely interventions to prevent further complications, potentially improving long-term outcomes for these patients.

Dr.Camel's Conclusion

This research is like a shimmering oasis in the vast desert of HIV treatment, providing valuable insights into the early detection of lipodystrophy. The study's findings are a beacon of hope, guiding us towards more effective management strategies for this challenging condition.

Date :
  1. Date Completed 2015-01-26
  2. Date Revised 2022-01-29
Further Info :

Pubmed ID

24717427

DOI: Digital Object Identifier

10.3851/IMP2695

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Languages

English

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