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Anthropometric measurements and lipid profiles to detect early lipodystrophy in antiretroviral therapy experienced HIV-infected children in the CHAPAS-3 trial.
Author: , AbongomeraGeorge, ArachBeatrice, AsiimweAlice R, CookAdrian, GibbDiana M, KabambaDesiree, KayiwaJoshua, KekitiinwaAdeodata, KennyJulia, KityoCissy, KleinNigel, KomunyenaJustine, MirembeGrace, MulengaVeronica, MusiimeVictor, NansubugaCarol, WalkerSarah A, WavamunnoPriscilla, ZangataDorothy
Original Abstract of the Article :
BACKGROUND: Few studies have investigated objective markers of lipodystrophy in African children. We compared body circumferences, skin-fold thickness (SFT) and lipids in antiretroviral therapy (ART)-naive and stavudine (d4T)-exposed children with HIV-uninfected controls. METHODS: In the CHAPAS-3 t...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.3851/IMP2695
データ提供:米国国立医学図書館(NLM)
Early Detection of Lipodystrophy: A Desert Oasis in HIV Treatment
The field of [HIV treatment] has made remarkable strides, but managing the long-term effects of [antiretroviral therapy (ART)] remains a critical challenge. This study investigated the potential of [anthropometric measurements] and [lipid profiles] as early indicators of [lipodystrophy] in [HIV-infected children]. The researchers compared these measures in [ART-naive] and [d4T-exposed] children to [HIV-uninfected controls]. Their findings suggest that specific anthropometric and lipid markers can signal the onset of lipodystrophy, allowing for early intervention and potentially mitigating long-term complications.
Early Detection: A Key to Effective Management
The results show that [ART-experienced] children on d4T-containing regimens had lower [skin-fold thickness] and higher [total cholesterol] and [low-density lipoprotein] levels compared to [ART-naive] children and [HIV-uninfected controls]. These findings highlight the importance of regular monitoring for early signs of lipodystrophy in children receiving ART.
Monitoring for Lipodystrophy: A Desert Oasis in HIV Treatment
This research underscores the need for vigilant monitoring of anthropometric and lipid profiles in HIV-infected children on ART. Early detection of lipodystrophy allows for timely interventions to prevent further complications, potentially improving long-term outcomes for these patients.
Dr.Camel's Conclusion
This research is like a shimmering oasis in the vast desert of HIV treatment, providing valuable insights into the early detection of lipodystrophy. The study's findings are a beacon of hope, guiding us towards more effective management strategies for this challenging condition.
Date :
- Date Completed 2015-01-26
- Date Revised 2022-01-29
Further Info :
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