Effect of long-acting gonadotropin-releasing hormone analog (leuprolide) therapy on prostatic size and symptoms in 15 men with benign prostatic hypertrophy.

Author: DrollerM, GabriloveJ L, KirschenbaumA, LevineA C

Paper Details 
Original Abstract of the Article :
To determine the effects of reversible medical castration on prostatic size and symptoms we treated 15 patients with benign prostatic hypertrophy with a long-acting GnRH analog, leuprolide (1 mg/day sc), for a minimum of 4 months. The men's serum testosterone, dihydrotestosterone, and estradiol conc...See full text at original site
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引用元:
https://doi.org/10.1210/jcem-69-3-629

データ提供:米国国立医学図書館(NLM)

Impact of Leuprolide on Prostatic Size and Symptoms

This research dives into the realm of

benign prostatic hypertrophy (BPH)

, a common condition that affects men. Like a skilled surgeon navigating the delicate terrain of the prostate, researchers investigated the effects of

leuprolide

, a long-acting

gonadotropin-releasing hormone (GnRH)

analog, on prostatic size and symptoms in men with BPH. Their findings demonstrate that leuprolide treatment significantly reduces prostatic size and improves urinary flow, leading to a decrease in obstructive symptoms. This study provides valuable insights into the potential of GnRH analogs for managing BPH and alleviating associated symptoms.

Shrinking the Prostate: A New Oasis in BPH Treatment

The study's findings, like a refreshing oasis in the desert of BPH treatment, showcase the potential of leuprolide for shrinking the prostate and relieving obstructive symptoms. The significant reduction in prostatic size and improvement in urinary flow observed in these men offer a promising avenue for managing BPH. However, it is crucial to consider the potential side effects, such as decreased potency and flushing, and to carefully monitor patients during treatment.

Navigating the Terrain of Prostate Health

This study serves as a valuable compass for men navigating the terrain of prostate health. The findings highlight the potential benefits of leuprolide for managing BPH and improving quality of life. However, it's important to remember that, like navigating a desert, it's crucial to choose the right path for each individual, considering their specific needs and potential risks.

Dr.Camel's Conclusion

This study underscores the potential of GnRH analogs, like leuprolide, for shrinking the prostate and improving urinary flow in men with BPH. However, it's important to be aware of potential side effects and to discuss treatment options with a medical professional to determine the best course of action.

Date :
  1. Date Completed 1989-09-15
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2474565

DOI: Digital Object Identifier

10.1210/jcem-69-3-629

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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