Effects of entecavir on peripheral blood lymphocyte profiles in chronic hepatitis B patients with suboptimal responses to adefovir.

Author: HuXiaoli, JiangYanfang, WangQuan, ZhangLiwen, ZhaoPingwei

Paper Details 
Original Abstract of the Article :
The aim of the present study was to assess the long-term impact of entecavir (ETV) on T, B and natural killer (NK) cell immunity in patients with suboptimal responses to adefovir (SRA) chronic hepatitis B (CHB). Thirty SRA CHB patients and 20 age- and gender-matched healthy controls (HC) completed a...See full text at original site
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引用元:
https://doi.org/10.1111/1440-1681.12245

データ提供:米国国立医学図書館(NLM)

Entecavir: A Powerful Weapon in the Fight Against Suboptimal Responses to Adefovir in Chronic Hepatitis B

This study explores the effectiveness of entecavir (ETV) in treating patients with chronic hepatitis B (CHB) who have suboptimal responses to adefovir (SRA). Think of CHB as a desert oasis threatened by a persistent drought, causing damage and weakening the body's defenses. The researchers investigate the impact of ETV on immune cell profiles in patients with SRA-CHB, seeking to understand its role in restoring immune function and combating the viral infection. The study found that ETV effectively inhibited HBV replication, improved liver function, and modulated T and NK cell immunity in patients with SRA-CHB, offering a glimmer of hope for individuals battling this challenging condition.

Entecavir: A Beacon of Hope in the Desert of Hepatitis B

The study highlights the potential of ETV to improve treatment outcomes for patients with CHB who experience suboptimal responses to adefovir. It's like discovering a new source of water in a desert, providing a much-needed boost to the body's defenses and combating the effects of the viral infection. The study's findings encourage the use of ETV as a valuable treatment option for patients with SRA-CHB, potentially improving their long-term health and quality of life.

Combatting Hepatitis B: A Journey Through the Desert of Immunity

This study reminds us of the importance of understanding the complex interplay between viral infections, the immune system, and drug therapies. It's like navigating a vast desert, where understanding the terrain and its inhabitants is key to survival. The study's findings encourage continued research into the treatment of CHB, emphasizing the need for effective therapies to combat this challenging condition.

Dr. Camel's Conclusion

This study delves into the complex world of hepatitis B treatment, showcasing the potential of entecavir to offer a lifeline for patients who have experienced suboptimal responses to other medications. It's like finding a hidden spring of life in the desert of hepatitis B, a source of hope for individuals seeking to overcome this challenging condition. The study's findings encourage the use of entecavir as a valuable treatment option, potentially leading to improved outcomes and a better quality of life for patients with chronic hepatitis B.
Date :
  1. Date Completed 2015-03-30
  2. Date Revised 2021-01-03
Further Info :

Pubmed ID

24773272

DOI: Digital Object Identifier

10.1111/1440-1681.12245

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English

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