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A randomized trial of the effectiveness of topical "ABH Gel" (Ativan(®), Benadryl(®), Haldol(®)) vs. placebo in cancer patients with nausea.

Author: CoynePatrick J, DodsonPatricia W, FletcherDevon S, ParkerGwendolyn G, SmithThomas J, WanWen

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

ABH gel, a topical gel containing lorazepam, diphenhydramine, and haloperidol, is often used for nausea but lacks scientific evidence for its effectiveness. Further research is needed to understand why it is perceived to be effective.
Paper Details　
Original Abstract of the Article :
The topical gel known as "ABH gel," comprising lorazepam (Ativan(®)), diphenhydramine (Benadryl(®)), and haloperidol (Haldol(®)), is frequently used to treat nausea because of its perceived efficacy, relatively low cost, and ease of use in the home setting. There are limited scientific data on this ...See full text at original site
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引用元：
https://doi.org/10.1016/j.jpainsymman.2014.02.010

データ提供：米国国立医学図書館（NLM）

The Mystery of ABH Gel: A Quest for Evidence in Cancer-Related Nausea

The [oncology] field is constantly seeking ways to alleviate the debilitating side effects of [cancer] treatment, particularly [nausea]. This research investigates the effectiveness of a topical gel known as 'ABH gel,' a mixture of [lorazepam], [diphenhydramine], and [haloperidol], in managing cancer-related nausea. The study aims to evaluate the efficacy of ABH gel compared to placebo in a randomized trial.

The Effectiveness of ABH Gel: Navigating the Desert of Nausea

This study reveals that ABH gel, despite its widespread use, lacks scientific support for its effectiveness in treating cancer-related nausea. The research found no evidence of absorption of the active ingredients of the gel, raising questions about the perceived efficacy of this treatment. The desert of cancer treatment is a challenging one, and finding effective and safe therapies is crucial for improving patient well-being.

The Need for Evidence-Based Approaches in Oncology: Seeking Oases of Hope

This research emphasizes the importance of evidence-based medicine in oncology. It highlights the need for rigorous scientific studies to evaluate the effectiveness of various treatments, including those that are widely used but lack strong scientific support. The desert of cancer treatment is vast and complex, but with a commitment to scientific rigor, we can pave the way for more effective and safe therapies that improve patient outcomes.

Dr.Camel's Conclusion

The findings of this study remind us that the desert of cancer treatment is a landscape full of mirages. While ABH gel has been a popular treatment for nausea, it lacks scientific evidence to support its effectiveness. This highlights the importance of relying on evidence-based medicine and conducting rigorous research to evaluate the efficacy of various therapies. The journey through this desert requires a commitment to scientific rigor and a dedication to finding oases of hope and healing for those facing cancer.

Date :
  1. Date Completed 2015-08-10
  2. Date Revised 2014-12-03
Further Info :

Pubmed ID

24793078

DOI: Digital Object Identifier

10.1016/j.jpainsymman.2014.02.010

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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