Combination antibiotic treatment versus monotherapy for multidrug-resistant, extensively drug-resistant, and pandrug-resistant Acinetobacter infections: a systematic review.

Author: FalagasM E, PoulikakosP, TansarliG S

Paper Details 
Original Abstract of the Article :
Controversy surrounds combination treatment or monotherapy against multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) Acinetobacter infections in clinical practice. We searched the PubMed and Scopus databases for studies reporting on the clinical outcomes of pat...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1007/s10096-014-2124-9

データ提供:米国国立医学図書館(NLM)

Combating Multidrug-Resistant Acinetobacter: A Desert of Challenges

Multidrug-resistant (MDR) Acinetobacter infections are a major threat to public health. It's like a relentless desert sandstorm, eroding our ability to control infections. This study reviewed the effectiveness of combination antibiotic treatment versus monotherapy for MDR Acinetobacter infections. They analyzed data from studies involving patients infected with MDR, extensively drug-resistant (XDR), and pandrug-resistant (PDR) Acinetobacter. Their findings suggested that combination treatment might be superior to monotherapy in certain cases, but further research is needed to confirm this.

Combination Treatment: A Double-Edged Sword

The study found that combination therapy might be more effective than monotherapy in treating MDR Acinetobacter infections, but this was not consistent across all studies. It's like finding a rare oasis in the desert, but with a hidden danger lurking nearby. Combination treatment can offer a more potent solution, but it also comes with increased risks, such as toxicity and the potential for resistance development.

Antibiotic Resistance: A Looming Threat

This study highlights the growing challenge of antibiotic resistance. It's like a desert slowly turning into a wasteland, where life-sustaining resources are becoming scarce. We need to be vigilant in developing new treatments and strategies to combat this threat. It's a race against time, just like a camel caravan trying to reach an oasis before the desert wind dries it up.

Dr. Camel's Conclusion

The fight against MDR Acinetobacter is a challenging one, but not insurmountable. We need to continue our research and develop new strategies to combat this threat. It's a journey across a vast desert, but with determination and innovation, we can find a way to overcome the challenges and ensure a healthier future.

Date :
  1. Date Completed 2015-06-01
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

24832022

DOI: Digital Object Identifier

10.1007/s10096-014-2124-9

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.