Safety and efficacy of the dipeptidyl peptidase-4 inhibitor linagliptin in elderly patients with type 2 diabetes: a comprehensive analysis of data from 1331 individuals aged ≥ 65 years.

Author: BarnettA H, HehnkeU, PatelS, SchernthanerG, WoerleH-J, von EynattenM

Paper Details 
Original Abstract of the Article :
AIMS: To investigate individual patient data from a comprehensive trials programme to evaluate the safety and efficacy of the dipeptidyl peptidase-4 (DPP-4) inhibitor linagliptin across a range of glucose-lowering regimens in a large elderly population with type 2 diabetes mellitus (T2DM). METHODS:...See full text at original site
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引用元:
https://doi.org/10.1111/dom.12321

データ提供:米国国立医学図書館(NLM)

Linagliptin: A Safe and Effective Treatment for Elderly Patients with Type 2 Diabetes

This research, focused on the

field of geriatric medicine and diabetes management

, investigates the safety and efficacy of linagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, in elderly patients with type 2 diabetes mellitus (T2DM). The study analyzed individual patient data from seven phase III clinical trials, encompassing a large cohort of elderly patients with T2DM. The authors found that linagliptin was well-tolerated and effectively improved glycemic control in elderly patients, demonstrating its suitability for this population.

Linagliptin: A Promising Option for Elderly Patients with T2DM

The study highlights the efficacy and safety of linagliptin in elderly patients with T2DM, suggesting its potential as a valuable therapeutic option for managing glycemic control in this population. The findings provide reassurance regarding the safety and effectiveness of linagliptin, particularly in relation to hypoglycemic events.

Type 2 Diabetes: Navigating Treatment in the Elderly

The study underscores the importance of selecting appropriate diabetes medications for elderly patients, considering their unique needs and susceptibility to side effects. The findings provide valuable insights into the safety and efficacy of linagliptin in this population, informing clinical decision-making and guiding treatment strategies.

Dr. Camel's Conclusion

Just as a camel adapts to the changing desert landscape, physicians must tailor their treatment approaches to meet the unique needs of elderly patients with T2DM. Linagliptin appears to be a suitable oasis in the desert of diabetes management for the elderly, offering a safe and effective path towards better glycemic control.

Date :
  1. Date Completed 2015-07-07
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

24865132

DOI: Digital Object Identifier

10.1111/dom.12321

Related Literature

SNS
PICO Info
in preparation
Languages

English

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