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Proniosome-derived niosomes for tacrolimus topical ocular delivery: in vitro cornea permeation, ocular irritation, and in vivo anti-allograft rejection.
Author: GeLi, GeShumin, LiQi, LiZhanrong, LiangDan, LuHaoyang, WuChuanbin, XuYuehong, ZengWeidong
Original Abstract of the Article :
The objective of this study was to develop proniosome-derived niosomes for topical ophthalmic delivery of Tacrolimus (FK506). The FK506 loaded proniosomes containing poloxamer 188 and lecithin as surfactants, cholesterol as a stabilizer, and minimal amount of ethanol and trace water reconstituted to...See full text at original site
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引用元:
https://doi.org/10.1016/j.ejps.2014.05.020
データ提供:米国国立医学図書館(NLM)
A New Frontier in Ocular Drug Delivery: Proniosome-Derived Niosomes for Tacrolimus
The field of [pharmaceutics] explores innovative approaches to [drug delivery] and aims to improve the efficacy and safety of [medications]. This research investigates the potential of [proniosome-derived niosomes] as a novel delivery system for [tacrolimus], a [immunosuppressant] used in [ophthalmology]. The authors demonstrate the effectiveness of [proniosome-derived niosomes] in enhancing [cornea permeation] and [drug retention] of [tacrolimus], suggesting their potential as a superior delivery vehicle for [ocular applications].
A Superior Delivery System for Tacrolimus: The Promise of Proniosome-Derived Niosomes
This research presents a compelling case for [proniosome-derived niosomes] as a promising delivery system for [tacrolimus]. The authors' findings demonstrate that these [niosomes] significantly enhance [cornea permeation] and [drug retention] compared to conventional [ointments], suggesting their potential to improve [tacrolimus] efficacy and reduce treatment frequency. These findings pave the way for a new era in [ocular drug delivery] characterized by enhanced effectiveness and patient convenience.
A Brighter Future for Ocular Health: Innovations in Drug Delivery
This study highlights the importance of [innovative drug delivery systems] in improving [ocular health]. The authors' exploration of [proniosome-derived niosomes] demonstrates the potential of [nanotechnology] to revolutionize [ocular drug delivery], leading to more effective treatments and improved patient outcomes. This research underscores the importance of [continuous research and development] in advancing the field of [ophthalmology] and improving the lives of patients with [ocular conditions].
Dr. Camel's Conclusion
Just as a camel can traverse the vast desert by carrying essential resources in its humps, researchers are developing innovative ways to deliver medications more effectively. This study demonstrates the promise of [proniosome-derived niosomes] as a superior delivery system for [tacrolimus], potentially improving treatment outcomes and enhancing the quality of life for patients with [ocular conditions].
Date :
- Date Completed 2015-03-30
- Date Revised 2014-07-21
Further Info :
Related Literature
English
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