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[Drug-induced immune hemolytic anemia: a retrospective study of 10 cases].

Author: BernardC, BollotteA, BriccaP, BroussolleC, SèveP, VialT

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Drug-induced immune hemolytic anemia (DIIHA) is a rare but serious condition that can be fatal. This study identified 10 cases of DIIHA, with causal drugs including ambroxol, beta-interferon, cefotetan, ceftriaxone, loratadine, oxacillin, oxaliplatine, piperacillin-tazobactam, pristinamycin, and quinine. The diagnosis is often difficult due to similarities with autoimmune hemolytic anemia and the inconsistent sensitivity of immunologic tests.
Paper Details　
Original Abstract of the Article :
PURPOSE: Drug-induced immune haemolytic anemia occurs in one case per million and can be fatal. Our aim was to describe the main characteristics and the type of drug involved. METHODS: Cases were retrospectively identified using spontaneous notifications collected by our pharmacovigilance centre an...See full text at original site
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引用元：
https://doi.org/10.1016/j.revmed.2014.05.009

データ提供：米国国立医学図書館（NLM）

Drug-Induced Immune Hemolytic Anemia: A Silent Threat

Drug-induced immune hemolytic anemia (DIIHA) is a rare but potentially life-threatening adverse drug reaction. This study examines 10 cases of DIIHA, highlighting the diverse range of drugs that can trigger this condition and the challenges associated with its diagnosis. The study emphasizes the importance of considering DIIHA in patients presenting with hemolytic anemia, especially after exposure to potential culprit drugs. The findings underscore the need for vigilant pharmacovigilance to ensure the safe use of medications.

Hidden Dangers: Unveiling the Silent Threat of DIIHA

This study sheds light on the hidden dangers of DIIHA, a rare but potentially life-threatening adverse drug reaction. The diverse range of drugs implicated in these cases underscores the importance of considering DIIHA in patients presenting with unexplained hemolytic anemia. Imagine a vast desert, where hidden dangers lurk beneath the surface. DIIHA is like a silent threat, lurking in the shadows of drug therapy. This study serves as a warning, reminding us to be vigilant and attentive to potential adverse reactions.

Navigating the Desert: A Call for Vigilance in Drug Therapy

This study emphasizes the importance of vigilant pharmacovigilance in ensuring the safe use of medications. The researchers highlight the challenges associated with diagnosing DIIHA and the need for a high index of suspicion in patients presenting with hemolytic anemia after drug exposure. It's like navigating a desert landscape, where a careful eye for detail and a cautious approach are essential for safe passage. This research reminds us to be alert to the potential for hidden dangers and to seek expert guidance when facing unexpected health challenges.

Dr.Camel's Conclusion

This study sheds light on the serious but often overlooked condition of drug-induced immune hemolytic anemia. It serves as a reminder of the potential dangers associated with medication use and the importance of vigilance in monitoring for adverse reactions. It's a journey through the desert of drug therapy, where we must be prepared to face the unexpected and seek expert guidance when needed.

Date :
  1. Date Completed 2015-08-13
  2. Date Revised 2016-10-18
Further Info :

Pubmed ID

24908632

DOI: Digital Object Identifier

10.1016/j.revmed.2014.05.009

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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