Formulation of extended release cefpodoxime proxetil chitosan-alginate beads using quality by design approach.

Author: AliMushir, KohliKanchan, MujtabaAli

Paper Details 
Original Abstract of the Article :
The purpose of this work was to develop and characterize chitosan-alginate beads for the extended delivery of cefpodoxime proxetil (CFP), to understand the impact of formulation and process parameters on the critical quality attributes (CQAs) using a quality-by-design approach. For this, a study was...See full text at original site
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引用元:
https://doi.org/10.1016/j.ijbiomac.2014.05.066

データ提供:米国国立医学図書館(NLM)

Cefpodoxime Proxetil: Delivering a Sustained Release

This study delves into the realm of pharmaceutical formulation, exploring the development of chitosan-alginate beads for the extended delivery of cefpodoxime proxetil (CFP), an antibiotic. The researchers employed a quality-by-design approach, meticulously investigating the influence of various formulation and process parameters on the critical quality attributes (CQAs) of the beads. The study successfully optimized the formulation, resulting in beads that release CFP in a sustained manner over a 24-hour period, fulfilling the requirements for extended drug delivery.

Cefpodoxime Proxetil: Sustained Release for Extended Efficacy

This study highlights the successful development of a sustained-release formulation for cefpodoxime proxetil, extending its therapeutic efficacy and potentially improving patient compliance. The researchers' approach, based on quality-by-design principles, ensures the development of a robust and reliable formulation.

Innovations in Drug Delivery: Improving Treatment Outcomes

This study underscores the importance of innovative drug delivery systems in enhancing treatment efficacy and patient care. The development of extended-release formulations like the chitosan-alginate beads for cefpodoxime proxetil holds significant potential for improving patient outcomes by optimizing drug delivery and extending therapeutic effects.

Dr. Camel's Conclusion

This study showcases the power of scientific innovation in the field of pharmaceuticals. The successful development of a sustained-release formulation for cefpodoxime proxetil highlights the dedication of researchers to improving drug delivery systems and ultimately enhancing patient care. This research represents a promising step toward more effective and convenient treatments for patients.
Date :
  1. Date Completed 2015-03-12
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

24915550

DOI: Digital Object Identifier

10.1016/j.ijbiomac.2014.05.066

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PICO Info
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Languages

English

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