Rivastigmine transdermal patch and physical exercises for Alzheimer's disease: a randomized clinical trial.

Author: AguiarPaula, FeresAna, GomesIrênio, MeloAilton, MonteiroLarissa

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To determine the effects of rivastigmine patch associated with physical exercise versus rivastigmine patch alone in quality of life (QOL), cognition, activities of daily living (ADL) and functional mobility in Alzheimer's disease (AD)subjects. METHODS: A randomized, controlled, single-bl...See full text at original site
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引用元:
https://doi.org/10.2174/1567205011666140618102224

データ提供:米国国立医学図書館(NLM)

Rivastigmine Patch and Physical Exercise for Alzheimer's Disease

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions worldwide, leading to cognitive decline and functional limitations. This study investigates the combined effects of rivastigmine, a medication used to treat AD, and physical exercise on quality of life (QOL), cognition, activities of daily living (ADL), and functional mobility in individuals with AD.

The researchers conducted a randomized controlled trial involving patients with mild to moderate AD, all of whom received rivastigmine transdermal patches. They were then randomly assigned to either a physical exercise group or a control group. The exercise program consisted of a combination of aerobic, flexibility, strength, and balance exercises twice a week for six months. The researchers monitored the patients' QOL, cognition, ADL, and functional mobility over the six-month period.

Exercise as a Complementary Treatment

The study found that after six months, patients in the physical exercise group showed a significant improvement in QOL compared to the control group. While there was no significant difference in cognitive function between the groups, the physical exercise group showed improvement in functional mobility, whereas the group receiving only rivastigmine showed a worsening in their ability to perform ADL.

Staying Active for Improved Quality of Life

This study suggests that combining physical exercise with rivastigmine therapy may lead to significant improvements in QOL for individuals with AD. While further research is needed to confirm these results, the study provides encouraging evidence for the potential benefits of incorporating regular physical activity into AD management. It's important to consult with a healthcare professional to determine the appropriate exercise regimen for your individual circumstances.

Dr.Camel's Conclusion

This study highlights the potential of physical exercise as a complementary therapy in the management of Alzheimer's disease. Just as a camel uses its powerful legs to traverse vast distances, physical exercise can help individuals with AD maintain mobility and improve their overall well-being. We must remember that healthy habits, such as exercise and proper nutrition, are crucial for overall health and can play a role in mitigating the impact of age-related conditions.

Date :
  1. Date Completed 2015-02-26
  2. Date Revised 2019-10-27
Further Info :

Pubmed ID

24938502

DOI: Digital Object Identifier

10.2174/1567205011666140618102224

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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