Paper Details

  1. Home
  2. Paper Details

Efficacy of intravenous propacetamol hydrochloride in the treatment of an acute attack of migraine.

Author: FangYannan, JiangTao, LuoYifeng, ShiXiaolei, XiaoZijian, ZhangAiwu, ZhengZhenyang

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A randomized controlled trial compared the efficacy of intravenous propacetamol to oral rizatriptan in treating acute migraine attacks. The study found that propacetamol was either equivalent or superior to rizatriptan in efficacy, with the advantage of parenteral administration for patients with nausea and vomiting.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Triptans are a family of selective serotonin (5-HT1B/1D) receptor agonists that are widely used to treat acute migraine attacks. Their efficacy is limited by side effects and the gastrointestinal manifestations of migraine. AIM: To compare the efficacy of a single intravenous administra...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.ejim.2014.06.007

データ提供：米国国立医学図書館（NLM）

Efficacy of Intravenous Propacetamol Hydrochloride in the Treatment of an Acute Attack of Migraine

Migraine, a debilitating condition, can feel like a desert storm raging through the mind. This study, published in [Journal Name], investigates the effectiveness of intravenous propacetamol, a prodrug of paracetamol, in treating acute migraine attacks.

Propacetamol Shows Promise for Migraine Relief

The researchers, like intrepid explorers seeking a cure in the desert, compared the efficacy of intravenous propacetamol to oral rizatriptan, a commonly used migraine medication, in treating acute migraine attacks. They found that intravenous propacetamol, like a cooling desert breeze, was either equivalent or superior to oral rizatriptan in reducing migraine pain, with significant improvements observed at 60 minutes after treatment.

Navigating the Challenges of Migraine Management

The study's findings suggest that intravenous propacetamol may offer a valuable alternative for patients with acute migraine attacks, particularly those experiencing nausea and vomiting. The study underscores the importance of developing effective and convenient treatment options for migraine sufferers, improving their quality of life and reducing the burden of this debilitating condition.

Dr. Camel's Conclusion

This research, like a well-stocked oasis in the desert, offers a potential solution for the challenges of managing acute migraine attacks. The findings suggest that intravenous propacetamol may be a valuable addition to the therapeutic arsenal for migraine treatment, potentially providing faster relief and improving the experience of patients navigating this challenging condition.
Date :
  1. Date Completed 2015-05-14
  2. Date Revised 2014-08-25
Further Info :

Pubmed ID

25002083

DOI: Digital Object Identifier

10.1016/j.ejim.2014.06.007

Related Literature

Article Analysis
・Side Effects of rizatriptan
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.