Paper Details 
Original Abstract of the Article :
Chloral hydrate (CH) is commonly used as a sedative and a hypnotic in pediatric medicine. In this study, the effects of CH on various developmental stages of Drosophila melanogaster were investigated. Different concentrations of CH (0.1; 0.3; 0.5 and 1 mg/mL) were used during development of the flie...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754252/

データ提供:米国国立医学図書館(NLM)

Chloral Hydrate: A Sedative's Impact on Development

Chloral hydrate, a commonly used sedative and hypnotic in pediatric medicine, has been a mainstay in the treatment of sleep disorders. This study investigates the potential developmental effects of chloral hydrate, delving into the intricacies of its impact on the life cycle of Drosophila melanogaster, a common model organism in biological research.

A Journey Through the Life Cycle of Drosophila

The researchers, like explorers venturing into the delicate ecosystem of a desert oasis, carefully studied the effects of chloral hydrate on different developmental stages of Drosophila. They found that exposure to chloral hydrate led to a delay in metamorphosis, a critical phase in the fly's life cycle. This is like a caravan encountering a drought, where the growth of desert plants is stunted and development is delayed. The study also observed a decrease in the total number of offspring, indicating a potential impact on reproductive success.

The Delicate Balance of Development

The study's findings highlight the importance of carefully considering the potential developmental risks associated with chloral hydrate, particularly in young and developing organisms. This is like navigating a fragile desert ecosystem, where even small changes in the environment can have significant and lasting impacts. The researchers emphasize the need for further research to understand the long-term effects of chloral hydrate on development and to explore alternative treatment options when possible.

Dr.Camel's Conclusion

This study sheds light on the potential developmental effects of chloral hydrate, a commonly used sedative. The findings underscore the importance of carefully considering the potential risks and benefits of this medication, especially in young and developing organisms. Like navigating a desert ecosystem, we must be mindful of the delicate balance of life and the potential consequences of our actions.

Date :
  1. Date Completed 2016-02-16
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

25098686

DOI: Digital Object Identifier

PMC4754252

Related Literature

SNS
PICO Info
in preparation
Languages

English

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