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Activity of benzimidazoles against Dientamoeba fragilis (Trichomonadida, Monocercomonadidae) in vitro and correlation of beta-tubulin sequences as an indicator of resistance.
Author: BarrattJoel L N, EllisJohn, HarknessJohn T, MarriottDeborah, RobertsTamalee, StarkDamien
Original Abstract of the Article :
Recently, Dientamoeba fragilis has emerged as a significant and common enteropathogen. The majority of patients with dientamoebiasis present with gastrointestinal complaints and chronic symptoms are common. Numerous studies have successfully demonstrated parasite clearance, coupled with complete res...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141546/
データ提供:米国国立医学図書館(NLM)
Unmasking the Mystery: Dientamoeba fragilis and the Challenge of Benzimidazoles
Dientamoeba fragilis, a microscopic parasite lurking in the desert of our digestive system, poses a significant health challenge. This study examines the effectiveness of benzimidazoles, a common class of antiparasitic drugs, against this elusive parasite. The researchers investigated the susceptibility of D. fragilis to various benzimidazoles, hoping to find a solution to this persistent problem.Benzimidazoles: An Oasis in the Desert of D. fragilis?
Unfortunately, the results were less than encouraging. The researchers found that none of the benzimidazoles tested were effective against D. fragilis, suggesting that this parasite may be more resilient than initially thought. This finding highlights the need for further research to identify new therapeutic strategies for treating D. fragilis infections.Navigating the Desert of D. fragilis: A Need for New Solutions
This research emphasizes the need for new approaches to combat D. fragilis infections. The failure of benzimidazoles, a common class of antiparasitic drugs, underscores the challenge of managing this parasite. Further research is crucial to find effective treatments for this increasingly prevalent pathogen.Dr.Camel's Conclusion
This study revealed that benzimidazoles, a common class of antiparasitic drugs, are not effective against D. fragilis. This highlights the need for new therapeutic strategies to combat this increasingly prevalent parasite. As researchers continue to explore the desert of D. fragilis, it's crucial to remain persistent in finding new solutions to this stubborn challenge.Date :
- Date Completed 2015-05-15
- Date Revised 2021-10-21
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