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Loxapine: a review of its pharmacological properties and therapeutic efficacy as an antipsychotic agent.

Author: AveryG S, BrogdenR N, HeelR C, SpeightT M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Loxapine is an antipsychotic medication used to treat schizophrenia. It has a similar effectiveness and side effect profile to other traditional antipsychotic agents. While it may be less effective than other antipsychotics in short-term studies, it is superior to placebo and as effective as other agents in long-term studies (4-12 weeks). Common side effects include extrapyramidal symptoms and sedation. Other less common side effects are similar to those seen with older antipsychotics.
Paper Details　
Original Abstract of the Article :
Loxapine is a dibenzoxazepine, tricyclic compound recommended for the treatment of acute and chronic schizophrenia. In its therapeutic effectiveness and profile and incidence of side-effects, loxapine closely resembles the traditional antipsychotic agents. Although loxapine has tended to be less eff...See full text at original site
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引用元：
https://doi.org/10.2165/00003495-197815030-00002

データ提供：米国国立医学図書館（NLM）

Loxapine: A Powerful Weapon in the Antipsychotic Arsenal

This study, published in 1981, dives into the world of antipsychotic medications, examining the properties and efficacy of loxapine, a medication used to manage schizophrenia, a complex mental illness. The researchers, like explorers navigating the vast desert of the brain, investigated loxapine's effectiveness in treating acute and chronic schizophrenia.

Loxapine: A Promising Antipsychotic

The study revealed that loxapine, like a powerful oasis in the desert, showed significant promise in treating schizophrenia, demonstrating comparable effectiveness to other traditional antipsychotic medications. However, it's important to note that loxapine, like a desert mirage, can also cause side effects, including extrapyramidal reactions, sedation, and anticholinergic effects.

Navigating the Desert of Schizophrenia

It is crucial to remember that every camel reacts differently to the desert's challenges. The right antipsychotic for you will depend on your individual needs and health history. Always consult with a healthcare professional to determine the most suitable treatment for your schizophrenia.

Dr. Camel's Conclusion

This study, like a caravan venturing into uncharted territory, provides valuable insights into the effectiveness of loxapine as an antipsychotic. The research highlights the potential of loxapine to provide relief for individuals with schizophrenia, offering a beacon of hope for those seeking treatment.
Date :
  1. Date Completed 1978-06-28
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

25167

DOI: Digital Object Identifier

10.2165/00003495-197815030-00002

Related Literature

Article Analysis
・Side Effects of loxapine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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