Comparative effectiveness of pharmacologic treatments to prevent fractures: an updated systematic review.

Author: BoothMarika J, CrandallCarolyn J, DiamantAllison, GelladWalid F, LimYee-Wei, MotalaAneesa, NewberrySydne J, ShekellePaul G

Paper Details 
Original Abstract of the Article :
BACKGROUND: Osteoporosis is a major contributor to the propensity to fracture among older adults, and various pharmaceuticals are available to treat it. PURPOSE: To update a review about the benefits and harms of pharmacologic treatments used to prevent fractures in adults at risk. DATA SOURCES: M...See full text at original site
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引用元:
https://doi.org/10.7326/M14-0317

データ提供:米国国立医学図書館(NLM)

Preventing Fractures: A Comparative Look at Pharmacologic Treatments

This comprehensive review examines the comparative effectiveness of various pharmacologic treatments for preventing fractures in adults at risk for osteoporosis. The researchers conducted a [systematic review of 315 articles] published between 2005 and 2014, evaluating the benefits and harms of different medications. They found strong evidence that [bisphosphonates, denosumab, and teriparatide] effectively reduce fracture risk compared to placebo.

Optimizing Fracture Prevention Strategies

The study provides valuable insights into the effectiveness of different medications for fracture prevention in individuals with osteoporosis. The researchers highlight the importance of [personalized treatment] based on individual risk factors and preferences. The review emphasizes the need for continued research to better understand the comparative effectiveness of different medications and to identify potential long-term side effects.

Building Stronger Bones

This study emphasizes the importance of [bone health] and the role of medications in reducing fracture risk. It underscores the need for [regular bone density screenings] and [early intervention] for individuals at risk for osteoporosis. This review provides valuable information for healthcare providers and patients in making informed decisions about fracture prevention strategies.

Dr.Camel's Conclusion

Imagine a desert oasis, a haven for weary travelers. This review is like that oasis, offering valuable information for navigating the challenges of osteoporosis and fracture prevention. The researchers have meticulously mapped the landscape of medication options, providing clear insights into their effectiveness and potential side effects. By understanding these options, individuals can make informed choices to protect their bones and maintain their mobility as they journey through life.

Date :
  1. Date Completed 2015-04-14
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

25199883

DOI: Digital Object Identifier

10.7326/M14-0317

Related Literature

SNS
PICO Info
in preparation
Languages

English

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