Superiority of ivermectin 1% cream over metronidazole 0·75% cream in treating inflammatory lesions of rosacea: a randomized, investigator-blinded trial.

Author: , Berth-JonesJ, JacovellaJ, OrtonneJ P, PeironeM H, RoszkiewiczJ, RuzickaT, TaiebA

Paper Details 
Original Abstract of the Article :
BACKGROUND: Few therapeutic alternatives currently exist in the treatment of papulopustular rosacea (PPR). OBJECTIVES: To demonstrate superiority of once-daily ivermectin 1% cream (IVM 1%) once daily vs. twice-daily metronidazole (MTZ 0·75%) cream, regarding percentage reduction of inflammatory les...See full text at original site
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引用元:
https://doi.org/10.1111/bjd.13408

データ提供:米国国立医学図書館(NLM)

Ivermectin vs. Metronidazole for Rosacea: A Camel's Tale of Two Treatments

The treatment of [papulopustular rosacea (PPR)] can be a challenging endeavor, requiring effective and well-tolerated therapies. This study compares the efficacy of [ivermectin 1% cream] to [metronidazole 0.75% cream] in treating moderate to severe PPR. The researchers conducted a [Phase 3, investigator-blinded, randomized, parallel-group study] and found that [ivermectin 1% cream was significantly superior to metronidazole 0.75% cream] in reducing inflammatory lesions, with improvement observed as early as week 3. Additionally, [ivermectin 1% cream demonstrated better local tolerability] than metronidazole.

A Camel's Oasis: Finding Relief from Rosacea

Imagine a desert traveler battling a persistent skin irritation. Two different ointments are offered, one providing a more effective and soothing relief. This analogy represents the study's findings, where ivermectin 1% cream emerged as the more effective and better-tolerated treatment for rosacea. This discovery brings hope for individuals seeking a more successful and comfortable path to managing their skin condition.

A Camel's Word of Encouragement

As a camel who has traversed the desert's harsh landscapes, I know the importance of finding the right treatment for skin conditions. While this study suggests the effectiveness of ivermectin 1% cream, it's essential to consult with a dermatologist to determine the best course of action for your individual needs. Remember, taking care of your skin is a crucial step in maintaining overall health and well-being.

Dr. Camel's Conclusion

Ivermectin 1% cream emerges as a beacon of hope for those seeking relief from the fiery sands of rosacea. Its superior efficacy and better tolerability offer a more comfortable and effective journey toward clear skin. While it might not be a universal solution, it represents a significant step forward in managing this common condition.

Date :
  1. Date Completed 2016-01-04
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

25228137

DOI: Digital Object Identifier

10.1111/bjd.13408

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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