Comparison of Effects of Different Dexmedetomidine and Chloral Hydrate Doses Used in Sedation on Electroencephalography in Pediatric Patients.

Author: BayramAyşe Kacar, CanpolatDilek Gunay, CanpolatMehmet, GumusHakan, KumandasSefer, PerHuseyin, PoyrazogluHatice Gamze, YildizKaramehmet

Paper Details 
Original Abstract of the Article :
The aim of this study was to compare the efficacy and safety of different oral chloral hydrate and dexmedetomidine doses used for sedation during electroencephalography (EEG) in children. One hundred sixty children aged 1 to 9 years with American Society of Anesthesiologists physical status I-II who...See full text at original site
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引用元:
https://doi.org/10.1177/0883073814549582

データ提供:米国国立医学図書館(NLM)

Sedation for EEG in Children: A Comparison of Dexmedetomidine and Chloral Hydrate

Electroencephalography (EEG) is a diagnostic test that measures brain activity. It's like a map of the brain's electrical activity, providing insights into its function. However, for children, getting a good EEG can be challenging, as they may be restless or uncooperative.

This research examines the efficacy and safety of two commonly used sedatives, dexmedetomidine and chloral hydrate, in children undergoing EEG. The researchers randomly assigned 160 children, aged 1 to 9 years, to four groups: two groups received dexmedetomidine at different doses (2 and 3 µg/kg), and two groups received chloral hydrate at different doses (50 and 100 mg/kg). The researchers assessed sedation time, EEG quality, and adverse effects.

The results demonstrate that dexmedetomidine was generally safe and effective for sedation during EEG in children. It was particularly effective in reducing anxiety and allowing for optimal EEG recordings. Chloral hydrate, while also effective, was associated with a significantly higher rate of adverse effects, particularly at the higher dose.

Dexmedetomidine: A Safer and More Effective Option for Pediatric Sedation

This research provides evidence supporting dexmedetomidine as a safer and more effective option for sedation during EEG in children compared to chloral hydrate. Its ability to provide adequate sedation with fewer adverse effects makes it a valuable tool for pediatric neurodiagnostics.

Navigating the Desert of Pediatric Sedation: Seeking the Right Approach

The desert of pediatric sedation can be tricky to navigate. This research highlights the importance of choosing the right sedation agent for each child, considering their individual needs and potential risks.

Dr. Camel's Conclusion

This research underscores the importance of careful sedation selection in pediatric EEG. Dexmedetomidine emerges as a safe and effective alternative to chloral hydrate, offering a gentler approach to sedation for young patients. Remember, like a wise camel traversing a desert, we must choose the path that best suits our needs and consider all available options to ensure a safe and successful journey.
Date :
  1. Date Completed 2016-03-15
  2. Date Revised 2022-04-10
Further Info :

Pubmed ID

25246305

DOI: Digital Object Identifier

10.1177/0883073814549582

Related Literature

SNS
PICO Info
in preparation
Languages

English

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